# Comparative Effectiveness Research & Cochrane Eyes and Vision (CEV)

> **NIH NIH UG1** · UNIVERSITY OF COLORADO DENVER · 2021 · $998,323

## Abstract

PROEJCT SUMMARY/ABSTRACT
Systematic reviews are comparative effectiveness research (CER) studies that use explicit methods to identify,
appraise, and synthesize available evidence for a clinical question. Cochrane is the only international
organization that has the goal of synthesizing and keeping up-to-date the evidence for all of healthcare.
Cochrane Eyes and Vision (CEV) aims to prepare and promote access to systematic reviews of interventions
used to prevent or treat eye conditions and/or visual impairment, and to help people adjust to visual impairment
or blindness. For 12 years, CEV United States Satellite (CEV@US) has overseen production of systematic
reviews and contributed to CER in eyes and vision in the US.
The CEV@US's organizational structure comprises an engaged Advisory Board, a leadership team
consisting of the PI and two senior Co-Investigators, and five interdependent workgroups who implement the
five Specific Aims with stakeholder partners. CEV@US is in a unique position to make a much-needed,
continued contribution to well-informed decisions about vision care, leading to real impact to preserving sight
and prevention of blindness.
Our objective is for CEV@US to continue to serve as the center for CER in eyes and vision in the US. In Aim
1, we will build a CER workforce within the field of vision science by educating health professionals. Our
education is flexible and tailored, and is offered online and in-person, via professional organizations, clinical
programs, and one-time workshops. In Aim 2, we will partner with individual (eg, clinicians, patients) and
organizational (eg, professional and specialty societies, academic medical centers, journals) stakeholders to
ensure that the knowledge underpinning clinical practice is reliable, available, and applied. Our partnership
strategy is multidimensional, unique and extensive, and offers a methodologic hub supporting clinician-authors
and researchers. In Aim 3: we will prepare systematic reviews that address prioritized questions in
collaboration with clinicians and methodologists, publish the reviews, and regularly update them as new
research emerges. We will work directly with clinicians and apply state-of-art methods in producing these
reviews. In Aim 4, we will conduct foundational methodologic research related to systematic reviews, and
influence the field of evidence synthesis. In Aim 5, we will disseminate the results of our research extensively.
Our dissemination strategy is designed to having an impact, using traditional and electronic means. All aims
taken together, our approach will leverage the collective expertise and perspectives of our stakeholder partners
and lead the effort to build a CER community.

## Key facts

- **NIH application ID:** 10200046
- **Project number:** 5UG1EY020522-13
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** Tianjing Li
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $998,323
- **Award type:** 5
- **Project period:** 2010-05-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10200046

## Citation

> US National Institutes of Health, RePORTER application 10200046, Comparative Effectiveness Research & Cochrane Eyes and Vision (CEV) (5UG1EY020522-13). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10200046. Licensed CC0.

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