# Pilot Projects Core

> **NIH NIH P30** · UNIVERSITY OF MINNESOTA · 2021 · $190,164

## Abstract

PROJECT SUMMARY: Pilot Projects Core
The primary goal of the proposed NIDA Center for Neural Circuits in Addiction is to extend and enhance the
research capabilities of NIH-funded addiction research projects at the University of Minnesota (UMN). The
proposed Viral Innovation Core (VIC), Imaging Cells during Behavior Core (ICBC), Structural Circuits Core
(SCC) and Addiction Connectome Core (ACC) will provide extensive technical expertise and infrastructure to
individual investigators. To complement these efforts, the Pilot Project Core (PPC) will provide necessary
means to foster new research and interactions by selecting and funding innovative projects that can
synergistically combine the capabilities of the Research Cores to push the envelope in neural circuit research.
The PPC, led by Center Director, Dr. Thomas, will engage a panel of Center faculty and External Advisors
(i.e. the Pilot Panel) who will review proposals and present finalists to the Steering Committee for final
determination. Following consultation with Program staff at NIDA, two to four projects will be funded each
fiscal year. Proposals will be reviewed in accordance with standard NIH review criteria (significance,
innovation, rigor and feasibility) and should address one or more of the following priorities: 1) ESIs; 2) New
entrants to addiction research; 3) Demonstrate translational potential; 4) Engage a team of PIs who have not
previously collaborated with one another; 5) Use Research Cores in a novel way; and/or 6) Develop substantial
new capabilities for one or more Research Cores. Inclusion of preliminary data is not required. Applications
for "bridge funds" or to extend ongoing projects will not be entertained. Finally, the Pilot Panel will also work
on research dissemination so that Center members have the opportunity on a regular basis to see specific
applications of Research Core functions, which we expect will stimulate creative new uses for these functions
and new collaborations.
The Core has two Specific Aims: Aim 1 will establish the Pilot Research Program with the first two recipient
teams. These include a project from New Investigators, Drs. Patrick Rothwell and Esther Krook-Magnuson
entitled: “Parsing Interneuron Diversity in the Nucleus Accumbens to Understand the Actions of Fentanyl” and
a project from Drs. Matthew Chafee, Benjamin Hayden, and Jan Zimmernann titled “Front-Parietal Circuit
Manipulation in Macaques.” Their team is composed of an ESI (Zimmermann) and two established investigators,
forming a new collaborative team. Proposed awards are $50k over a period of up to two years. In Aim 2, the
Pilot Panel, in consultation with the Steering Committee, will establish and maintain infrastructure, policies and
procedures for award selection, ongoing evaluation and research dissemination of innovative pilot projects.

## Key facts

- **NIH application ID:** 10200737
- **Project number:** 5P30DA048742-02
- **Recipient organization:** UNIVERSITY OF MINNESOTA
- **Principal Investigator:** Mark John Thomas
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $190,164
- **Award type:** 5
- **Project period:** 2020-07-01 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10200737

## Citation

> US National Institutes of Health, RePORTER application 10200737, Pilot Projects Core (5P30DA048742-02). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10200737. Licensed CC0.

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