# Michigan Lupus Epidemiology and Surveillance (MILES) Program Longitudinal Cohort & Biobank

> **NIH ALLCDC U01** · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2021 · $900,000

## Abstract

PROJECT SUMMARY/ABSTRACT
This proposal is to continue longitudinal follow-up of lupus cases and controls in the population-based
Michigan Lupus Epidemiology & Surveillance (MILES) Program Cohort and Biobank. The overarching goal is
to prospectively collect data and biospecimens that will allow for comprehensive investigations of risk factors
related to lupus and disease progression, as well as underlying disparities. We are currently in a third wave of
cohort study visits. Detailed data collection encompasses measures related to four core content areas:
natural history, treatment, healthcare access and disparities. The state-of-the-art biobank includes whole
blood, serum, plasma, DNA/RNA (from lymphocyte subsets), urine, hair, and toenail clippings. Biobank
specimens are processed and stored in appropriate conditions to provide the capacity to perform assays
including contemporary immunoassays, biomarkers of disease and exposures, genotyping, and DNA
methylation of relevant lymphocyte subsets. Major thematic areas that the MILES Cohort & Biobank is
designed to support include environmental and nutritional epidemiology, epigenetics, and health services
research. The MILES Cohort will thus serve as a robust platform for ongoing and future research
investigations that are relevant to the full spectrum of lupus and its complications.

## Key facts

- **NIH application ID:** 10201405
- **Project number:** 5U01DP006489-03
- **Recipient organization:** UNIVERSITY OF MICHIGAN AT ANN ARBOR
- **Principal Investigator:** Emily Catherine Somers
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** ALLCDC
- **Fiscal year:** 2021
- **Award amount:** $900,000
- **Award type:** 5
- **Project period:** 2019-09-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10201405

## Citation

> US National Institutes of Health, RePORTER application 10201405, Michigan Lupus Epidemiology and Surveillance (MILES) Program Longitudinal Cohort & Biobank (5U01DP006489-03). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10201405. Licensed CC0.

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