# Biomedical Informatics Core

> **NIH NIH U54** · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2021 · $325,064

## Abstract

PROJECT SUMMARY: BIOMEDICAL INFORMATICS (BMI) CORE
The mission of the Biomedical Informatics (BMI) Key Component Activity (KCA) of the Louisiana Clinical and
Translational Science Center (LA CaTS) is to develop and deploy “state of the art” biomedical informatics
capabilities and services across all partner institutions, in support of clinical and translational research aimed at
improving health outcomes and addressing disparities in our most vulnerable populations. Over the past 4
years, the BMI KCA supported 55 LA CaTS Investigators across 14 institutions, resulting in 27 publications and
7 funded grant applications. During the next funding period, the BMI KCA will pursue several innovative goals:
1) the creation of i2b2-searchable “virtual cohorts” for diseases disproportionately affecting Louisiana patients;
2) the participation in the Southeast SHRINE and TriNetX clinical data networks; 3) the integration of genomic,
pathologic and clinical datasets; and 4) the creation of a searchable “virtual biorepository” linking physical
biorepositories across LA CaTS institutions. We will leverage key collaborations with: PCORI-funded
REACHnet; UAB- and Medical University of South Carolina (MUSC)-led CTSA Centers; the Precision Medicine
and Bioinformatics Programs at LSUHSC-New Orleans, and the Louisiana Tumor Registry (LTR). We are
excited about expanding our services to our LA CaTS new partner institutions: the LSUHSC Dental and
Nursing Schools, the Southeast Louisiana Veterans Healthcare System, the University Medical Center in New
Orleans and Ochsner Health System. To accomplish our mission, we propose the following aims:
Specific Aim 1. To significantly expand ongoing BMI services and to build on our experience to develop novel
analytical tools for data mining, precision medicine and molecular epidemiology.
Specific Aim 2. To expand our ability to enable meaningful collaboration and data sharing between LA CaTS
Investigators and Louisiana-based Louisiana Biomedical Research Network (LBRN) and Centers of Biomedical
Research Excellence (COBRE) Centers, and between LA CaTS Investigators and CTSA Centers regionally
and nationally, and to increase cyber access to underserved populations.
Specific Aim 3. To provide continued, coordinated support for project design and implementation and
professional development, in close cooperation with the Clinical Research Resources (CRR), Design,
Epidemiology and Biostatistics (DEB), Cyberinfrastructure Enhancement (CE), Professional Development
(PD), Ethics and Regulatory Knowledge (ERKC) and Health Literacy (HL) KCAs.

## Key facts

- **NIH application ID:** 10201622
- **Project number:** 5U54GM104940-06
- **Recipient organization:** LSU PENNINGTON BIOMEDICAL RESEARCH CTR
- **Principal Investigator:** Lucio Miele
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $325,064
- **Award type:** 5
- **Project period:** 2012-08-15 → 2022-08-04

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10201622

## Citation

> US National Institutes of Health, RePORTER application 10201622, Biomedical Informatics Core (5U54GM104940-06). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10201622. Licensed CC0.

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