# Trajectories of Behavioral Inhibition and Risk for Anxiety

> **NIH NIH U01** · UNIV OF MARYLAND, COLLEGE PARK · 2020 · $107,455

## Abstract

The parent grant, Trajectories of behavioral inhibition and risk for anxiety (U01MH093349), examines the
developmental pathways from early fearful temperament, Behavioral Inhibition (BI), to anxiety emerging during
late adolescence. Although BI is one of the best early predictors for later anxiety, not all children with a history
of BI go on to develop clinically significant anxiety, making it critical to identify the mechanisms that
differentiate adolescents who struggle from those who adapt. To understand variability in outcomes, the parent
grant examines how specific internal (e.g., reactive vs proactive cognitive control) and external (e.g.,
supportive friendships) factors, assessed during mid-adolescence (age 15), serve to exacerbate or mitigate
responses to social challenges. Finally, the parent grant examines the link between response to social
challenges at age 18 and the development of psychopathology by late adolescence (age 18), within a large
sample of adolescents. Specifically, social interactions between the target participants and unfamiliar peers are
observed, information regarding social relationships is obtained, and psychiatric status is evaluated. This
administrative supplement requests funds for subject compensation so that we may conduct the social
interactions, administer questionnaires regarding social relationships and evaluate psychiatric status on-line as
opposed to in the lab.

## Key facts

- **NIH application ID:** 10201969
- **Project number:** 3U01MH093349-10S1
- **Recipient organization:** UNIV OF MARYLAND, COLLEGE PARK
- **Principal Investigator:** Nathan A Fox
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $107,455
- **Award type:** 3
- **Project period:** 2011-06-07 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10201969

## Citation

> US National Institutes of Health, RePORTER application 10201969, Trajectories of Behavioral Inhibition and Risk for Anxiety (3U01MH093349-10S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10201969. Licensed CC0.

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