Aging and mixed perturbation training to reduce falls in locomotion

NIH RePORTER · NIH · R01 · $322,084 · view on reporter.nih.gov ↗

Abstract

 DESCRIPTION (provided by applicant): The long-term objective of this research is to develop an efficacious training paradigm to enhance older adults' defense mechanisms against falls and possibility reduce healthcare cost. The Centers for Disease Control and Prevention estimates the direct medical cost for fall related injuries to be $30 billion annually. Slips and trips combied account for more than 50% of the outdoor falls in community-dwelling older adults. These environmental perturbations are opposing in nature, with slips mainly resulting in backward falls and trips in forward falls. This project explores perturbation training through both slip and trip exposure based on the principles of motor learning. The project design consists of a randomized controlled trial to examine the ability of the central nervous system to mitigate the interference in stability control (if any) that is induced by opposing types of perturbations. It aso introduces a novel combined slip and trip perturbation training paradigm to enhance one's ability to retain and generalize the acquired fall-prevention skills to both types of falls. Slips and trip induced on an over ground walkway will be used to prepare the motor system to improve stability control and vertical limb support to resist falls. The longer-term benefits of such combined perturbation training over exclusive slip-only or trip-only perturbation training in reducing both laboratory-induced and real life falls will also be assessed. The hypothesis of this study if supported by the results will provide an evidence-supported training protocol to reduce the fall-risk among community-dwelling older adults.

Key facts

NIH application ID
10204866
Project number
5R01AG050672-05
Recipient
UNIVERSITY OF ILLINOIS AT CHICAGO
Principal Investigator
Tanvi Bhatt
Activity code
R01
Funding institute
NIH
Fiscal year
2021
Award amount
$322,084
Award type
5
Project period
2016-09-01 → 2024-05-31