# Pittsburgh Center for Kidney Research

> **NIH NIH P30** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2021 · $590,769

## Abstract

The critical role of the kidney in maintaining homeostatic balance, and the disorders of
homeostasis that accompany diseases of the kidney and the associated loss of kidney function
underscore the importance of this organ in human health. Recent developments in biomedical
sciences have led to significant advancements in our understanding of the pathogenesis of
specific renal diseases, which have important diagnostic and therapeutic implications. The Aim
of our Pittsburgh Center for Kidney Research is to develop and facilitate multidisciplinary
research, training and information transfer related to kidney function in normal and disease
states. The major goals of our center are (i) to advance our knowledge base regarding normal
kidney function, cellular mechanisms that contribute to kidney disease and the many altered
cellular functions that occur in the settings of acute kidney injury and chronic kidney disease; (ii)
to facilitate early-phase translational investigation, including studies using animal models,
studies directed at drug discovery, development and pharmacokinetics, as well as support for
analytical studies; and (iii) to provide the expertise, training and equipment needed to facilitate
research activities in these areas. Center Core facilities support the work of one hundred and
eleven investigators at the University of Pittsburgh, the Icahn School of Medicine at Mount Sinai,
and at other institutions throughout the United States. Core A is a Physiology Core, led by Drs.
Carattino and Satlin. Core B is an Animal and Translational Core, led by Drs. Jackson and
Stocker. Core C is a Kidney Imaging Core, led by Dr. Apodaca. Core D is a Model Systems and
Therapeutics Core, led by Drs. Brodsky and Hukriede. The Center supports four pilot and
feasibility projects. An Administrative Core, led by Drs. Kleyman and Weisz, provides
administrative oversight of the core facilities, the pilot and feasibility project program and the
educational activities of the center. All research cores are specifically structured to serve as
national resources for investigators. Our Center is designed to realize our goal of continuing to
advance our understanding of normal renal function, of cellular mechanisms that contribute to
kidney disease, and of the many altered cellular functions that occur in the settings of acute
kidney injury and chronic kidney disease.

## Key facts

- **NIH application ID:** 10205029
- **Project number:** 5P30DK079307-14
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** Thomas R Kleyman
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $590,769
- **Award type:** 5
- **Project period:** 2008-09-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10205029

## Citation

> US National Institutes of Health, RePORTER application 10205029, Pittsburgh Center for Kidney Research (5P30DK079307-14). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10205029. Licensed CC0.

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