# Northern New England Clinical and Translational Research Network

> **NIH NIH U54** · MAINEHEALTH · 2021 · $3,961,510

## Abstract

PROJECT SUMMARY
The mission of the Northern New England Clinical and Translational Research (NNE-CTR) Network is to
develop and sustain a clinical and translational research infrastructure that supports improvement in rural and
community health for inhabitants in the IDeA states of Maine, New Hampshire and Vermont. This goal will be
accomplished through complementary and synergistic collaborations of investigators in two lead institutions,
Maine Medical Center (a member of the MaineHealth System) and
the University of Vermont (
with the
University of Vermont Health Network
), one participating institution, the University of Southern Maine, and two
collaborating organizations, the Dartmouth SYNERGY Clinical and Translational Science Institute and the
Dartmouth Primary Care Cooperative Research Network (Dartmouth CO-OP).
The Northeast has the largest
percentage of residents over 65 years of age, and while NNE-CTR will support clinical and translational studies
of all types, our efforts will emphasize health problems endemic in the rural populations of northern New
England, including cancer, cardiovascular disease, and substance abuse, as well as the barriers that
compromise rural health care delivery. The members of our proposed network have a long history of
collaboration, providing a solid platform for the proposed network. To accomplish these goals, NNE-CTR
proposes four specific aims: 1) improve the infrastructure and support for clinical and translational research in
Maine, New Hampshire and Vermont; 2) increase translational and clinical research capacity and efficacy by
establishing collaborative and synergistic transdisciplinary research partnerships among the NNE-CTR
institutions, aided by a vigorous Pilot Projects program; 3) establish innovative training, mentoring and
professional development programs to develop clinical and translational scientists at the NNE-CTR institutions;
and 4) provide the infrastructure to support community practices and practice-based primary care research
networks, particularly in rural areas, to engage clinical, community, public health and other stakeholders in the
development and conduct of research relevant to the clinical and population health needs of northern New
England. To achieve these aims, NNE-CTR will establish the following Key Component Activities:
Administrative Core; Pilot Projects Program; Professional Development Core; Clinical Research Design,
Epidemiology and Biostatistics Core; Rural Health Research and Delivery Core; Translational Research
Technologies Core; and the Tracking and Evaluation Core. In summary, by developing the capabilities and
resources required for research spanning the broad spectrum of clinical and translational science, the NNE-
CTR will provide the platform for enhancing clinical research and health care delivery to support the unique
needs of rural northern New England.

## Key facts

- **NIH application ID:** 10205083
- **Project number:** 5U54GM115516-05
- **Recipient organization:** MAINEHEALTH
- **Principal Investigator:** CLIFFORD JAMES ROSEN
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $3,961,510
- **Award type:** 5
- **Project period:** 2017-07-03 → 2022-08-04

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10205083

## Citation

> US National Institutes of Health, RePORTER application 10205083, Northern New England Clinical and Translational Research Network (5U54GM115516-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10205083. Licensed CC0.

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