# Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social

> **NIH NIH UH3** · UNIVERSITY OF WASHINGTON · 2020 · $294,760

## Abstract

ABSTRACT
Children are inherently shaped by the environment in which the live, learn, and play. This proposal to study the
impact of SARS-CoV-2 (COVID-19) virus outbreak on children’s development brings together a multidisciplinary
team of investigators across the country from 6 ECHO Awards, representing 5 cohorts of ~2500 middle childhood
and adolescent youth and the Person-Reported Outcome (PRO) Core). The proposed research develops and
tests a novel conceptual model that casts family and community sociodemographic risk as important factors that
shape COVID-19 related school, family, and child hardships and resources that influence child positive health.
We propose that school resources (e.g., type and quality of distance learning), family hardships (e.g., financial
strain and technology access), and child emotional support (e.g., connections to peers and family support)
combine to predict children's positive health as measured by academic competence and psychological well-
being. This ECHO proposal combines both variable-centered and person-centered methodological approaches
to generate critical, time-sensitive knowledge on modifiable and actionable factors that can effectively mitigate
the impact of COVID-19 psychosocial hardships on child positive health development. As school districts,
communities, and states begin planning for the next stages of economic opening and return from school closures
in the fall, it is imperative to know which children are most vulnerable and at-risk of being left behind; how school
policies and teaching approaches can be best optimized; and what social and emotional supports need to be in
place in order for families and communities to “build back better.”

## Key facts

- **NIH application ID:** 10205408
- **Project number:** 3UH3OD023271-05S1
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** Nicole Renee Bush
- **Activity code:** UH3 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $294,760
- **Award type:** 3
- **Project period:** 2016-09-21 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10205408

## Citation

> US National Institutes of Health, RePORTER application 10205408, Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social (3UH3OD023271-05S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10205408. Licensed CC0.

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