PROJECT SUMMARY We seek acceptance of our predoctoral biotechnology training program, which has a history of producing accomplished leaders in academia and industry. Biotechnology is broadening and evolving as a field with an expansion of knowledge, tools, and applications. In parallel, industry is shaping new efforts using biotechnology for prevention, diagnosis, and treatment of disease. Stanford provides an unusually rich environment, with co-located, nationally ranked schools devoted to basic science, engineering, and medicine, and a strong industrial presence from the surrounding Bay Area. We are leveraging this ecosystem to train talented students who are becoming the next-generation of interdisciplinary global biotechnology innovators, and who will lead and invent the future with integrity and rigor. We are seeking training funding for 10 trainees per year for a period of 5 years. The program fuses 39 investigators from 9 departments across at the university into a highly visible program that delivers a unique, applications-oriented training experience focused on health-related biotechnology. Differentiating features of this program include curricular offerings in biotechnology innovation and leadership, industrial internships, field trips, symposia, and deep interactions among trainees and academic and industrial mentors.