# Predoctoral Training in Stroke and its Co-Morbidities

> **NIH NIH T32** · WEST VIRGINIA UNIVERSITY · 2021 · $294,737

## Abstract

Project Summary
Stroke - like many brain diseases - is clearly associated with aging and a plethora of age-related
co-morbid conditions, including cognitive decline, Alzheimer’s disease (AD), multi-infarct
dementia, cardiovascular disease, cerebrovascular disease, hypertension, hypercholesterolemia,
immune suppression, metabolic syndrome and obesity, sleep deprivation, and depression.
However, age-related co-morbid conditions, as a variable in stroke occurrence, severity and long-
term recovery is seldom studied experimentally, but is one of the identified factors in the lack of
progress in the discovery of new therapies for acute stroke brain damage. To optimize the impact
of our research on the discovery of new preventatives, acute treatments and rehabilitation
methods for stroke, we need to train the next generation of stroke researchers to assess stroke
in the context of the affected patent population: those who are elderly and have multiple co-morbid
conditions. The Stroke and Its Co-morbidities Predoctoral Training Program will formalize and
standardize our already strong training programs in the biomedical sciences and focus on stroke
research. A number of innovative aspects of this training program are semester-long didactic
courses in “Stroke” and the “Neurobiology of Aging”, a clinical immersion in our WVU Stroke
Center, a Neuroscience Emerging Research Discoveries in Stroke (NERDS) journal club, an
Associate Scholars Program, and experience in community engagement. The proposed training
program will select the best PhD students from the participating Biomedical Sciences Training
programs at the West Virginia University (WVU) Health Science Center (WVU HSC) and will
prepare them with the skills, knowledge and acumen needed for a successful career in stroke
research. The specific training for each of 6 mentee will be tailored based on their annually
updated Individualized Development Plan (IDP), and an “Exploring Career Paths” Program will
help prepare them for their chosen career. Program training is expected to last 2-to-3 years. This
pre-doctoral training program will create a new generation of young scholars who can address
the need for innovative stroke research for the citizens of West Virginia and the nation.

## Key facts

- **NIH application ID:** 10212200
- **Project number:** 5T32AG052375-05
- **Recipient organization:** WEST VIRGINIA UNIVERSITY
- **Principal Investigator:** JAMES W. SIMPKINS
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $294,737
- **Award type:** 5
- **Project period:** 2017-05-01 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10212200

## Citation

> US National Institutes of Health, RePORTER application 10212200, Predoctoral Training in Stroke and its Co-Morbidities (5T32AG052375-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10212200. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*