Conduct of studies to evaluate the toxic potential of N-BUTYLBENZENE SULFONAMIDE (NBBS) in laboratory animals for the National Toxicology Program (NTP)

NIH RePORTER · NIH · N01 · $800,000 · view on reporter.nih.gov ↗

Abstract

The goal of this project is to evaluate the subchronic, reproductive, developmental and neurobehavioral toxicity of NBBS following exposure in dosed feed. These studies are in the pathology/data analysis/reporting phase. There is extensive used of NBBS and its toxicity database is limited. It is a common plasticizer and high production volume chemical. The limited toxicity data suggest multiple targets. The NTP studies will provide valuable data to on a wide variety of endpoints to provide a thorough evaluation of potential hazards. Keywords: toxicity, neurobehavioral, developmental, reproductive, dosed feed, N-BUTYLBENZENE SULFONAMIDE.

Key facts

NIH application ID
10213569
Project number
273201700005C-P00008-9999-8
Recipient
BATTELLE MEMORIAL INSTITUTE
Principal Investigator
BARNEY SPARROW
Activity code
N01
Funding institute
NIH
Fiscal year
2020
Award amount
$800,000
Award type
Project period
2017-09-26 → 2020-09-25