Evaluation of Conjugated VesiVax Formulations for HIV Vaccines

NIH RePORTER · NIH · N43 · $299,961 · view on reporter.nih.gov ↗

Abstract

Co-delivery and Formulation of Adjuvants for HIV Vaccine Development: Co-delivery of adjuvants with HIV antigens combined with HIV immunogen design is not mutually exclusive and should converge to accelerate the development of safe and effective adjuvanted HIV vaccine candidates that are capable of effective B/T-cell activation, enhanced antibody avidity or broadening of effector immune responses while minimizing reactogenicity and preserving the protective immune responses against HIV. The primary goal is to support, accelerate and advance early stage and/or pre-clinical development and optimization of a promising HIV antigen-adjuvant formulation or select combination-adjuvant(s) for co-delivery/co-administration for a preventative HIV vaccine.

Key facts

NIH application ID
10214865
Project number
75N93020C00010-0-9999-1
Recipient
MOLECULAR EXPRESS, INC.
Principal Investigator
SAM ON HO
Activity code
N43
Funding institute
NIH
Fiscal year
2020
Award amount
$299,961
Award type
Project period
2020-06-01 → 2021-05-31