# University of Washington HUB Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN)

> **NIH NIH U24** · UNIVERSITY OF WASHINGTON · 2021 · $117,235

## Abstract

The purpose of this proposal is to improve public health through the creation of a large-scale network of
prehospital and hospital care that will conduct pragmatic clinical trials addressing emergency medical
conditions affecting brain, heart, lung and/or blood as well as life-threatening trauma. The components of this
proposal include King County Emergency Medical Services (KCEMS) in concert with the University of
Washington and its Harborview and University Medical Centers. This “Hub” will both participate in these
clinical trials and provide administrative and academic oversight and leadership over additional community-
based facilities in the Pacific Northwest, and an additional academic facility (the University of British Columbia
in Vancouver, BC), which will serve as enrolling sites (or “Spokes”) for the conduct of these clinical trials. This
proposal strictly creates the network infrastructure for these anticipated trials, and not the trials themselves,
which are as yet not known. These trials, when forthcoming, will themselves require independent regulatory
approval which is anticipated to occur through a Central Institutional Review Board that will be created once
the network itself is established.

## Key facts

- **NIH application ID:** 10215627
- **Project number:** 5U24NS100654-05
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** Peter James Kudenchuk
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $117,235
- **Award type:** 5
- **Project period:** 2017-07-15 → 2023-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10215627

## Citation

> US National Institutes of Health, RePORTER application 10215627, University of Washington HUB Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) (5U24NS100654-05). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10215627. Licensed CC0.

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