# Building sequencing capacity to address nosocomial infections in primary care and referral veterinary medical facilities

> **NIH FDA U18** · OHIO STATE UNIVERSITY · 2020 · $161,556

## Abstract

PAR-18-604 Vet-LIRN Network Capacity-building Proposal
Project Summary/Abstract
The impact of antimicrobial resistance (AMR) in veterinary medicine, as in human healthcare, is
widespread and can often include negative patient outcomes and increased treatment costs. Resistant
bacteria can contaminate hospital environments and can pose a public health risk of zoonotic
transmission. Antimicrobial stewardship programs (ASP) have become the foundation for responding to
the antimicrobial resistance crisis in human healthcare, but ASPs in veterinary practice remain significantly
undeveloped. At the Ohio State University College of Veterinary Medicine (OSU-CVM), we began
developing a Veterinary ASP for our OSU Veterinary Medical Center (OSU-VMC) in 2015. The OSU-CVM
BuckeyeASP now provides a framework based on our successful existing program that can be adapted to
private veterinary practice. In fall 2020, the BuckeyeASP, a three-year certification program will be offered
without cost by the OSU-CVM Antimicrobial Stewardship Working Group (ASWG) to private veterinary
practices in Ohio. The program will be promoted by the OSU-CVM and the Ohio Veterinary Medical
Association (OVMA). Two primary components of the BuckeyeASP, are the active surveillance of hospital
environments and the passive surveillance of clinical isolates recovered from veterinary patients. The
three main aims of this proposal are 1) understand the molecular epidemiology of nosocomial infections
in primary care and referral veterinary medical facilities in Ohio; 2) establish the impact of veterinary
antimicrobial stewardship and infection control program implementation on the patient risk of
nosocomial infection in primary care veterinary practices, and 3) create and disseminate antimicrobial
stewardship and infection control recommendations for primary care veterinary practices in Ohio. We
propose to purchase automated equipment to improve our pathogen sequencing capacity and compile
data on nosocomial AMR infections in veterinary medicine. In addition, the Clinical Diagnostic Laboratory
of the VMC at Ohio State will adopt emerging technologies currently used to investigate nosocomial
infections as well as foodborne illness outbreaks. The adoption of these new technologies will allow the
laboratory to train personnel, participate in proficiency tests offered by the Vet-LIRN, and most
importantly, to support the network in case investigations when needed.

## Key facts

- **NIH application ID:** 10215997
- **Project number:** 1U18FD007232-01
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** Dubraska V Diaz-Campos
- **Activity code:** U18 (R01, R21, SBIR, etc.)
- **Funding institute:** FDA
- **Fiscal year:** 2020
- **Award amount:** $161,556
- **Award type:** 1
- **Project period:** 2020-09-20 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10215997

## Citation

> US National Institutes of Health, RePORTER application 10215997, Building sequencing capacity to address nosocomial infections in primary care and referral veterinary medical facilities (1U18FD007232-01). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10215997. Licensed CC0.

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