# Core B: Human Tissue and Genomics Core

> **NIH NIH P01** · UNIV OF NORTH CAROLINA CHAPEL HILL · 2021 · $253,810

## Abstract

Human Tissue and Genomics Core Summary
The overall objective of the Core is to provide resources and expertise to perform and analyze data
from gene expression, miRNA expression, ChIP-seq, and microbiota profiling assays that identify
disease-specific transcriptional patterns and shifts in microbiota abundance in tissue of patients with
IBD. Additionally, the Core will enable project investigators to perform functional validation in patient-
derived organoid experimental systems to substantiate and guide their hypotheses obtained in patient
samples and animal models. This will be facilitated through access to human samples from well-
characterized adult and pediatric IBD patients and controls.

## Key facts

- **NIH application ID:** 10216238
- **Project number:** 5P01DK094779-08
- **Recipient organization:** UNIV OF NORTH CAROLINA CHAPEL HILL
- **Principal Investigator:** SHEHZAD Z. SHEIKH
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $253,810
- **Award type:** 5
- **Project period:** 2013-09-19 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10216238

## Citation

> US National Institutes of Health, RePORTER application 10216238, Core B: Human Tissue and Genomics Core (5P01DK094779-08). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10216238. Licensed CC0.

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