# Harnessing the power of experimental genetic crosses and systems genetics to probe drug resistance in malaria

> **NIH NIH P01** · UNIVERSITY OF NOTRE DAME · 2021 · $93,045

## Abstract

ABSTRACT
The Administrative Core (Admin Core) based at the University of Notre Dame (UND) will ensure that the
Program Project grant (P01) PI and Admin Core Director (AD)(Ferdig) is positioned to supervise and
administer the P01. The Admin Core will facilitate communication and interaction between all groups and will
thus ensure that the three physically separate sites will function as a virtual single site. The AD, with assistance
from the Admin Core Program Manager (PM), will function to coordinate the overall scientific direction and will
monitor ongoing productivity of the P01 and communicate the activities to the Advisory Boards. In its
administrative capacity, the Admin Core will centralize program-wide information, provide administrative
support to program investigators, and maintain records relating to P01 progress. Ferdig will participate and
manage at all levels of communication and is responsible for all aspects of effective operations and
collaborative decision-making with the Leadership Team (LT).
The AD, with the assistance of a PM and the LT, consisting of all Project Leads and Core Directors, will
function to centralize program-wide information and to coordinate the overall direction of the P01 with feedback
from an Internal Advisory Board (IAB) and an External Advisory Board (EAB). The IAB will evaluate ongoing
progress towards P01 goals and provide recommendations for alternative strategies to P01 activities if
modifications are indicated. Members of the IAB will consist of distinguished expert faculty at the three
performance sites (UND, Texas Biomed and CID Research). The EAB will guide and evaluate the overall
impact and productivity of the program in alignment with the broader scientific community in the areas of the
P01. The EAB will be formed in communication with NIH Program advisors and will consist of worldwide
experts on classical genetics, linkage mapping, systems biology, malaria and drug resistance.

## Key facts

- **NIH application ID:** 10216642
- **Project number:** 5P01AI127338-05
- **Recipient organization:** UNIVERSITY OF NOTRE DAME
- **Principal Investigator:** Michael T Ferdig
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $93,045
- **Award type:** 5
- **Project period:** 2017-08-01 → 2024-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10216642

## Citation

> US National Institutes of Health, RePORTER application 10216642, Harnessing the power of experimental genetic crosses and systems genetics to probe drug resistance in malaria (5P01AI127338-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10216642. Licensed CC0.

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