# RCMI@Morgan: Center for Urban Health Disparities Research and Innovation

> **NIH NIH U54** · MORGAN STATE UNIVERSITY · 2020 · $188,750

## Abstract

PROJECT SUMMARY
Similar to HIV and hepatitis C virus, SARS-CoV-2, the cause of COVID-19, is most devastating to people of
health disparity populations (HDP). However, we hypothesize that COVID-19 could cause health disparities
among different HDP (i.e. “disparities within”) and certain circumstances and determinants could contribute to
and predict the “disparities within”. Our ongoing partnerships with a multi-hospital healthcare system and a
multisite community health center for the study of HIV/HCV-related health disparities provide an immediate,
practical, and pertinent platform to study the impacts of COVID-19 on health outcomes and healthcare access
and utilization among people of various HDP. The hospitals of the healthcare system and the clinics of the
community health center are situated in urban, suburban, and rural areas with major health disparities. The
healthcare system has provided SARS-CoV-2 testing services and treated many hospitalized COVID-19
patients. The community health center provides HIV care to people of racial/ethnic and sexual/gender minorities
and other vulnerable populations. We will take advantage of the ongoing partnerships, using a retrospective
cohort study design with data from the medical records, to dissect the “disparities within” caused by COVID-19.
First, we will delineate the clinical features and natural history of COVID-19 among the hospitalized patients, and
determine the factors associated with COVID-19 pathogenesis, disease severity, and treatment effectiveness.
We also aim to establish novel, unique, and tailored clinical “scoring” systems/models that can be used to predict
COVID-19 outcomes and severity in patients of different HDP. Second, we will analyze the trends in and
characteristics of the SARS-CoV-2 testing and assess whether people of the HDP were underrepresented in the
testing. We will also analyze the factors associated with SARS-CoV-2 positivity among those tested. For those
who tested positive, we will assess their participation/engagement in the COVID-19 cascade of care and
determine the factors associated with attending or missing each of the stages in the care cascade. Next, we will
assess the HIV continuum of care during the COVID-19 lockdown, analyzing the trends and factors associated
with missing appointments, labs, and/or prescriptions as well as the utilization of telehealth. We will also examine
the HIV-related health outcomes among those who continued care during the lockdown. Finally, we will perform
questionnaire surveys or interviews to assess the experiences and perceptions of (1) COVID-19 patient care
from the frontline healthcare workforce and (2) the pros and cons of telehealth in HIV care from the HIV patients
and care providers. We will also evaluate how the COVID-19 pandemic has changed/shaped the perception and
career/specialty choice of the medical residents, interns, and students. The results from this project will help
reduce the health disparities caused by COV...

## Key facts

- **NIH application ID:** 10216666
- **Project number:** 3U54MD013376-02S2
- **Recipient organization:** MORGAN STATE UNIVERSITY
- **Principal Investigator:** Hongtao Yu
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $188,750
- **Award type:** 3
- **Project period:** 2019-07-31 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10216666

## Citation

> US National Institutes of Health, RePORTER application 10216666, RCMI@Morgan: Center for Urban Health Disparities Research and Innovation (3U54MD013376-02S2). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10216666. Licensed CC0.

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