# Biostatistics Shared Resource

> **NIH NIH P30** · WASHINGTON UNIVERSITY · 2021 · $300,566

## Abstract

BIOSTASTICS SHARED RESOURCE (BSR): PROJECT SUMMARY
The Biostatistics Shared Resource (BSR) provides Siteman Cancer Center (SCC) research programs with
access to cancer-focused statistical expertise, including design of early phase clinical trials, longitudinal data
analysis, biomarker discovery, statistical methods for high dimensional genomic data, and risk prediction/risk
stratification development and validation. BSR statisticians are integrally involved in all seven SCC research
programs with 142 SCC member users in 2018. They function as scientific collaborators in clinical trial and
interventional protocols; advising on, and participating in, study design, creating and managing research
databases, overseeing statistically relevant issues in trial/project implementation, conducting interim and final
data analyses, presenting research data/methods, and interpreting results. BSR contributes to research rigor
and reproducibility through active involvement in scientific review and oversight activities. In collaboration with
the SCC Clinical Trials Core (CTC), BSR statisticians develop study-specific data collection forms and conduct
data monitoring. BSR faculty serve on the SCC Protocol Review and Monitoring Committee (PRMC) and the
SCC Quality Assurance and Safety Monitoring Committee (QASMC), providing statistical reviews of all new
protocols and assuring proper statistical conduct of all active protocols. BSR faculty collaborate on numerous
National Cancer Institute-funded projects and have contributed significantly to the high quality science and
research productivity of SCC programs. In the current project period alone, BSR faculty have authored over
250 peer-reviewed statistical methodology and cancer-related publications with 44 in high-impact journals
(Thomson Reuters impact factor of 10 or greater). This contribution illustrates the wide range of research and
methodologic expertise available to SCC members through the BSR. In the next project period, BSR will
continue to grow with increased capacity in statistical support for electronic health record-based comparative
effectiveness research, cancer immunotherapeutic trials, biomarker studies, and precision medicine initiatives.

## Key facts

- **NIH application ID:** 10217004
- **Project number:** 5P30CA091842-20
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** TIMOTHY J. EBERLEIN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $300,566
- **Award type:** 5
- **Project period:** 2001-08-02 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10217004

## Citation

> US National Institutes of Health, RePORTER application 10217004, Biostatistics Shared Resource (5P30CA091842-20). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10217004. Licensed CC0.

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