# Small Animal Cancer Imaging

> **NIH NIH P30** · WASHINGTON UNIVERSITY · 2021 · $327,406

## Abstract

SMALL ANIMAL CANCER IMAGING (SACI) SHARED RESOURCE: PROJECT SUMMARY
With the revolution in molecular biology, transgenic animal models – in particular mice – have become an
indispensable part of the cancer research armamentarium. The Siteman Cancer Center’s (SCC) Small Animal
Cancer Imaging (SACI) Shared Resource (SR) (initially established under the auspices of the NCI’s Small Animal
Imaging Resource Program) addresses the need for nondestructive imaging and analysis of small animal
laboratory models of cancer. It provides state-of-the-art facilities and infrastructure for magnetic resonance
imaging, positron emission tomography, X-ray computed tomography, single-photon emission computed
tomography, and optical (including Cerenkov) imaging of mice, rats, and other small laboratory animals that
serve as models of cancer.
 SACI combines instrumental and intellectual capabilities found at few other institutions and serves a broad
community of cancer scientists who have a pressing need for quantitative image analysis of small animal
model systems. The principal functions of SACI are to provide SCC members: i) access to, and maintenance
of, small animal magnetic resonance, nuclear medicine, and optical imaging scanners for cancer research; ii)
technology expertise and consultation in study design, protocol development, and data analysis/interpretation.
In addition to supporting cancer research applications of small animal imaging, SACI also provides research
and development at the frontier of imaging technology in an effort to make the most powerful new imaging
strategies available to its community of users. The SR is organized around three modality-specific imaging
components: (i) nuclear medicine, (ii) magnetic resonance, and (iii) optical. An overarching goal is translation to
the clinic of imaging protocols and therapeutic agents developed and validated with small animal models. Thus,
SACI directly supports the mission of the SCC by supporting basic discovery cancer research and cancer
imaging protocols with translational potential.

## Key facts

- **NIH application ID:** 10217012
- **Project number:** 5P30CA091842-20
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** TIMOTHY J. EBERLEIN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $327,406
- **Award type:** 5
- **Project period:** 2001-08-02 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10217012

## Citation

> US National Institutes of Health, RePORTER application 10217012, Small Animal Cancer Imaging (5P30CA091842-20). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10217012. Licensed CC0.

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