# Administrative and Statistical Core Resource

> **NIH NIH U54** · CHILDREN'S HOSP OF PHILADELPHIA · 2020 · $184,000

## Abstract

CORE A SUMMARY/ABSTRACT 
 Our proposed U54 Center application entitled Discovery and Development of Optimal Immunotherapeutic 
Strategies for Childhood Cancers is a multi-disciplinary and multi-institutional effort that we think is directly 
responsive to the RFAs designed to create the Pediatric Immunotherapy Discovery and Development Network 
(PI-DDN). Built on years of multi-disciplinary collaboration amongst Project and Core Principal Investigators 
and their research teams, we plan to directly address critical unmet needs uniquely relevant to children with 
high-risk cancers. To accomplish our Center goals, we propose experienced leadership to define priorities, 
sustain momentum and deliver results that meet defined milestones on time and under budget. The proposed 
co-PIs Drs. Maris and Mackall have worked together to lead complex research programs and coordinate 
integrated and collaborative experimentation. Here, we propose an administrative Core that will provide the 
scientific, statistical and administrative leadership to achieve the mission of the proposed investigation. With 
experienced statistical and administrative support, we will organize the recurring meetings and day-to-day 
operation of the Center and interactions with the PI-DDN and other immunotherapy efforts. The Core will 
support the scientific interchange necessary for the ambitious scientific goals of each Project and the Center as 
a whole, encourage input from pediatric cancer advocates to help shape our mission, oversee the allocation of 
budget on a quarterly basis as our research evolves, assure regulatory compliance, and promote experimental 
rigor and transparency.

## Key facts

- **NIH application ID:** 10217468
- **Project number:** 3U54CA232568-01S1
- **Recipient organization:** CHILDREN'S HOSP OF PHILADELPHIA
- **Principal Investigator:** JOHN M MARIS
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $184,000
- **Award type:** 3
- **Project period:** 2018-09-20 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10217468

## Citation

> US National Institutes of Health, RePORTER application 10217468, Administrative and Statistical Core Resource (3U54CA232568-01S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10217468. Licensed CC0.

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