# Core 3: Biostatistics and Bioinformatics

> **NIH NIH P50** · VANDERBILT UNIVERSITY MEDICAL CENTER · 2021 · $291,783

## Abstract

PROJECT SUMMARY/ABSTRACT: Biostatistics and Bioinformatics Core
The purpose of the Biostatistics and Bioinformatics Core (BBC) is to provide professional expertise in
biostatistics and bioinformatics for all Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal (GI) Cancer
projects, investigators, and participants. Functions provided by this core include development of experimental
designs, power analysis and sample size estimation, data quality control, statistical/bioinformatics analysis and
interpretation of findings, and collaboration on presentation of results. To achieve these functions, the core
director and core members are constantly available to investigators, with key biostatisticians and
bioinformaticians assigned to each project, and all are in regular contact with the project and core leaders.
The primary objectives of the BBC are:
1. To provide study design and review all laboratory, animal, translational, epidemiological, and clinical
 studies including feasibility assessment, power analysis, and sample size estimation;
2. To collaborate in project data analysis including bioinformatic pre-processing analysis, interpretation of
 results, and the writing of final study reports and manuscripts;
3. To work with the Tissue Pathology and Cellular Analysis Core and Mouse and Human Molecular Imaging
 Core in the development of research project databases, to maintain data quality control and to ensure
 timely data capture;
4. To develop and evaluate statistical/bioinformatic methods for experimental design and data analysis.
BBC support is required in all VICC GI Cancer SPORE studies, with biostatisticians and bioinformaticians
assigned to each project. Core personnel have worked and will continue to work closely with project leaders to
ensure the core provides state-of-the-art statistical /bioinformatic support.

## Key facts

- **NIH application ID:** 10218108
- **Project number:** 5P50CA236733-03
- **Recipient organization:** VANDERBILT UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** Yu Shyr
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $291,783
- **Award type:** 5
- **Project period:** 2019-07-09 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10218108

## Citation

> US National Institutes of Health, RePORTER application 10218108, Core 3: Biostatistics and Bioinformatics (5P50CA236733-03). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10218108. Licensed CC0.

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