# Histology, Microscopy and Image Analysis Core

> **NIH NIH P30** · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2021 · $148,000

## Abstract

PROJECT SUMMARY
The Histology, Microscopy and Image Analysis Core is designed to meet the needs of
Promising Junior Investigators, Pilot Project Researchers, and Funded Diabetes Investigators
by assisting them in studying diabetic human and animal tissues utilizing state-of-the-art
histologic and microscopic technologies, as well as assisting them with and providing them with
a variety of types of microscopy required for in vitro cellular microscopic analysis. Tissue
preparation requires a specialized laboratory and equipment, while state-of-the-art microscopes
are outside the budget of most laboratories. The objective of the HMIA Core is twofold. One is
to centralize histological preparation of tissues and provide access to specialized equipment for
preparing and cutting tissues. The second is to maintain and provide training on and access to a
variety of different types of state-of-the-art microscopes and to quantitative image analysis
software. The core will provide tissue processing, embedding, sectioning, and histochemical
staining of mounted slides, for both paraffin embedded and cryo-preserved tissue preparations.
In addition, the core will provide quality state-of-the-art instrumentation and expertise for
investigators to obtain microscopic images of publication quality using bright field, phase
contrast, and Nomarski DIC microscopy, epifluorescence microscopy, confocal and multi-photon
microscopy, laser capture microdissection microscopy, and live-cell imaging microscopy. To
complement the microscopy component of this Core, assistance and training with a variety of
quantitative image analysis tools is provided. The signup, billing, and tracking of Core use is all
done using iLabs software. The Core comprises 500 sq ft on the 5th floor of the Biomedical
Sciences Building for the histology functions and 150 sq ft on the 2nd floor of the Biomedical
Research Building for imaging functions. A business plan is in place so that by the end of the
COBRE Phase III the core will be financially stable and ready to integrate into the OUHSC
Research Core Facilities network.

## Key facts

- **NIH application ID:** 10219293
- **Project number:** 5P30GM122744-05
- **Recipient organization:** UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- **Principal Investigator:** JAMES J TOMASEK
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $148,000
- **Award type:** 5
- **Project period:** 2017-07-01 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10219293

## Citation

> US National Institutes of Health, RePORTER application 10219293, Histology, Microscopy and Image Analysis Core (5P30GM122744-05). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10219293. Licensed CC0.

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