# Center for Environmental and Health Effects of PFAS

> **NIH NIH P42** · NORTH CAROLINA STATE UNIVERSITY RALEIGH · 2020 · $542,111

## Abstract

Abstract
The NC State Center for Environmental and Health Effects of PFAS focuses on understanding
the implications of PFAS exposure in humans and animals in the Cape Fear River Basin of
North Carolina. The Cape Fear River in North Carolina is characterized by high levels of a
variety of PFAS (per-and poly-fluoroalkyl substances) throughout the watershed. The specific
chemicals vary by location with the lower Cape Fear characterized by the presence of novel
fluoroethers from chemical manufacturing near Fayetteville, NC, while upstream, the levels of
legacy PFAS such as PFOA and PFOS are elevated and frequently exceed the drinking water
advisory levels for these chemicals. To better characterize the diversity of PFAS exposures
among impacted communities along the Cape Fear River, we have developed this supplement
proposal to: 1) further characterize human exposure in communities upriver from Fayetteville, 2)
expand analytical capabilities to measure total organic fluorine in biological and environmental
samples, and 3) demonstrate feasibility for novel blood collection methods that can be
employed in the field for both human and animal blood PFAS analysis.

## Key facts

- **NIH application ID:** 10221364
- **Project number:** 3P42ES031009-01S2
- **Recipient organization:** NORTH CAROLINA STATE UNIVERSITY RALEIGH
- **Principal Investigator:** Carolyn J. Mattingly
- **Activity code:** P42 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $542,111
- **Award type:** 3
- **Project period:** 2020-02-28 → 2025-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10221364

## Citation

> US National Institutes of Health, RePORTER application 10221364, Center for Environmental and Health Effects of PFAS (3P42ES031009-01S2). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10221364. Licensed CC0.

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