# Bioinformatics Core

> **NIH NIH U54** · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2021 · $38,033

## Abstract

Project Summary 
The PDTC Biostatistics and Bioinformatics Core is a key integration point of the PDTC, and will provide the 
expertise to not only interpret complex “omics” data that is already associated with each of our PDX models, but 
also the expertise to identify molecular features of tumors that positively or negatively correlate with drug 
responses. The goals of the PDTC Biostatistics and Bioinformatics Core are: 
 1. To provide statistical modeling for experimental design, particularly with respect to animal preclinical trials 
 and their analyses, for both Research Projects and Pilot Projects. 
 2. To collaborate in research projects’ data analysis, interpretation of results, and the writing of final study 
 reports and manuscripts. 
 3. To develop standard practices for experimental design and analytics that can be implemented at HCI and 
 BCM, and across the PDXNet. 
 4. Perform primary and secondary analysis of genomic data, identification of statistically significant 
 changes, and data organization and distribution. 
 5. To facilitate data exchange between HCI and BCM, and across the PDXNet. 
 6. To maximize use of existing support for the two existing institutional cores at HCI and BCM in support of 
 patient-derive organoid (PDO) and PDX-based work, including software and database development. 
!

## Key facts

- **NIH application ID:** 10223228
- **Project number:** 5U54CA224076-04
- **Recipient organization:** UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH
- **Principal Investigator:** Kenneth Michael Boucher
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $38,033
- **Award type:** 5
- **Project period:** 2017-09-25 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10223228

## Citation

> US National Institutes of Health, RePORTER application 10223228, Bioinformatics Core (5U54CA224076-04). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10223228. Licensed CC0.

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