# Molecular Histopathology Analytical Microscopy Core (MHAM)

> **NIH NIH P20** · LSU HEALTH SCIENCES CENTER · 2021 · $32,689

## Abstract

ABSTRACT
The Molecular Histopathology and Analytical Microscopy Core (MHAM) was created to provide advanced
histopathology and microscopy services to researchers and clinicians conducting research at LSUHSC,
including promising junior investigators (PJIs) of the Center for Translational Viral Oncology (CTVO). The
MHAM provides PJIs with experimental planning design and imaging studies on the histology of tissues, the
expression of cell surface and intracellular macromolecules including viral proteins, using state-of-the-art bright
field, and confocal microscopy, immunohistochemistry, immunohistofluorescence, in situ hybridization, and in
situ proximity ligation (DuoLink). These multiple methods are also used to determine protein and mRNA levels,
their subcellular localization, protein-protein and RNA-protein interactions in the cells and tissues. Given the
translational nature of the CTVO, this core is led by a trained pathologist, Dr. Luis Del Valle who, in addition to
offering imaging services, also provides histopathological information and evaluation on patient tissues. The
MHAM, working in close collaboration with the new HIV/Clinical Tumor Biorepository (HCTB) core will provide
PJI's with access to clinical samples that are crucial to investigate the molecular and cellular pathways in virus-
induced cancers. Moreover, the MHAM core provides investigators with training on tissue processing and
management and assists investigators develop the necessary imaging and data for the submission of
manuscripts and grants.

## Key facts

- **NIH application ID:** 10223345
- **Project number:** 5P20GM121288-05
- **Recipient organization:** LSU HEALTH SCIENCES CENTER
- **Principal Investigator:** Luis Del Valle
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $32,689
- **Award type:** 5
- **Project period:** 2017-08-15 → 2022-07-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10223345

## Citation

> US National Institutes of Health, RePORTER application 10223345, Molecular Histopathology Analytical Microscopy Core (MHAM) (5P20GM121288-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10223345. Licensed CC0.

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