# Core C - Pathology

> **NIH NIH P30** · UNIVERSITY OF KENTUCKY · 2021 · $191,250

## Abstract

The Phase III Pathology Core has evolved from a need for specialized expertise in assessing the morphology
of adipose tissue as a link between obesity and cardiovascular diseases. The Core has developed extensive
expertise in tissue processing, paraffin embedding sectioning and basic stains for adipose tissue as well as
many other tissues from a range of species. The Phase III Pathology Core will continue to provide centralized
services for basic histology procedures and imaging, simplifying and standardizing the collection of pathology
data. Within Phase III, this core will build upon experience and expand equipment capabilities with an updated
embedding center, provision of immunostaining services, and through partnering with the Center for Clinical
and Translational Sciences (CCTS) Biospecimens Core Biobank. This Biobank collects several tissues,
including adipose tissue from several locations, from humans to speed the pace of translational studies.
During Phase II of the COCVD, this core performed 376 projects (to date) for 42 investigators, processing
>6000 samples, embedding >4700 samples, and sectioning >3600 sections to generate almost 30,000 slides.
In year 8 of the current program, this core has provided services to more than 150 projects, and routinely
services more than 50 projects/year. With expanded services, by partnering with the CCTS to serve as a
pathology conduit for investigators wishing to analyze human tissue morphology, and with an expansion of the
focus of the COCVD to include obesity as a risk factor for type 2 diabetes, cancer and neurodegenerative
diseases, we anticipate that increased demand for the services of this core will transition the core to self-
sustaining capacity.

## Key facts

- **NIH application ID:** 10225372
- **Project number:** 5P30GM127211-04
- **Recipient organization:** UNIVERSITY OF KENTUCKY
- **Principal Investigator:** WENDY S KATZ
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $191,250
- **Award type:** 5
- **Project period:** 2018-08-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10225372

## Citation

> US National Institutes of Health, RePORTER application 10225372, Core C - Pathology (5P30GM127211-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10225372. Licensed CC0.

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