# Improving Outcomes for Latinos on Hemodialysis with Limited English Proficiency

> **NIH NIH K23** · DENVER HEALTH AND HOSPITAL AUTHORITY · 2021 · $120,179

## Abstract

PROJECT SUMMARY/ABSTRACT
Latinos with End-Stage Renal Disease (ESRD) represent 17% of the US adult ESRD community and
compared to non-Latino whites, they are 1.6 times more likely to develop depressive affect. Depressive affect
among ESRD patients is associated with a reduced Health-Related Quality of Life (HRQOL), reduced renal
therapy adherence, greater morbidity, and increased mortality. In addition, depressive affect is adversely
affected by Limited English Proficiency (LEP) and many other social factors. With support from the Amos
award from the Robert Wood Johnson Foundation (RWJF), Dr. Lilia Cervantes assessed the feasibility of a 5-
visit lay Peer Navigator intervention to support Latino ESRD patients with social challenges and to activate
them to seek mental healthcare. Her peer navigator intervention is feasible; however, her research showed
that two-thirds of Latino ESRD patients with limited English proficiency report depressive affect yet do not seek
care due to cultural preferences and language barriers. The proposed study will build on her Amos RWJF
work by expanding the peer navigator intervention to include a bilingual Licensed Clinical Social Worker
(LCSW) that will provide individual dialysis Chairside Cognitive Behavioral Therapy (CCBT) sessions while the
peer navigator provides support with social factors. This patient-centered approach is culturally tailored and
will bridge the gap to mental health services. The overall aims of this proposal are to: 1) engage key
operational and clinical stakeholders early-on to develop a Peer Navigator-Licensed Clinical Social Worker
(PN-LCSW) intervention; 2) conduct a pilot RCT of the PN-LCSW intervention versus standard care to test
feasibility and acceptability; and 3) assess the efficacy of the intervention on depressive affect (primary
outcome) as well as health-related quality of life and hemodialysis adherence (secondary outcomes). The
candidate for this K23, Dr. Lilia Cervantes, is a 1st generation bilingual Latina and her long-term objective is
to be an independent physician investigator and leader developing culturally tailored models of care for Latino
ESRD patients with limited English proficiency to improve patient-centered and clinical outcomes. This K23
will provide Dr. Cervantes with the training to develop expertise in: 1) key stakeholder engagement; 2) clinical
trial design; and 3) analysis of patient-centered and clinical outcomes including longitudinal data and mediation
analysis. Dr. Cervantes will accomplish her research and training aims in the rich and supportive environment
at the University of Colorado Anschutz Medical Center and Denver Health with the support from her excellent
primary mentor Dr. Michel Chonchol (nephrology). Dr. Cervantes will make a significant contribution toward
improving patient-centered and clinical outcomes among vulnerable populations with ESRD and limited English
proficiency while obtaining the experience and training necessary to begin ...

## Key facts

- **NIH application ID:** 10226145
- **Project number:** 5K23DK117018-04
- **Recipient organization:** DENVER HEALTH AND HOSPITAL AUTHORITY
- **Principal Investigator:** Lilia Cervantes
- **Activity code:** K23 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $120,179
- **Award type:** 5
- **Project period:** 2018-09-15 → 2022-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10226145

## Citation

> US National Institutes of Health, RePORTER application 10226145, Improving Outcomes for Latinos on Hemodialysis with Limited English Proficiency (5K23DK117018-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10226145. Licensed CC0.

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