# Implementation and Evaluation at Northwestern Medicine of Shareable EHR Treatment Plans in support of Multi-Site Clinical Trials

> **NIH NIH P30** · NORTHWESTERN UNIVERSITY · 2021 · $302,248

## Abstract

The Robert H. Lurie Comprehensive Cancer Center (LCC) at Northwestern University recognizes that
implementation for clinical trial treatment plans in the Electronic Health Record (EHR) is an impediment to timely
activation of clinical trials of all sources, including the NCTN. LCC clinical trial and informatics experts are poised
to work with peers in other NCI-supported Cancer Centers to develop tools and standard processes to streamline
and harmonize EHR treatment plan development for multi-site clinical trials. This effort will require the careful
analysis of existing treatment plans to establish a common information model. The information model can be
used to create a single instance of EHR treatment plans which can then be quickly adopted by participating sites
for their local context. We plan to leverage the established partnerships within the Big Ten Cancer Research
Consortium and the proposed Big Ten Electronic Health Record Consortium for tackling this challenge in
coordination with the NCI and with EHR vendors. Specifically, we will: (1) Analyze previous treatment plans to
develop a global site-agnostic information model for representing EHR treatment plans in collaboration with the
Big Ten-EHRC and to identify the attributes that are specific for implementation of EHR treatment plans at LCC
and its largest clinical affiliate, Northwestern Medicine (NM); (2) Participate in the communal development of
novel toolkits that expedite the activation of NCTN clinical trials using harmonized EHR implementation of
treatment plans. This will be achieved by contribution of expert effort – clinical trialists and informaticists –
towards technical development, and by piloting the implementation of global informatics artifacts in local LCC
and NM systems; and (3) Prospectively validate this EHR treatment plan implementation both locally at NM and
globally across the collaborating institutions.

## Key facts

- **NIH application ID:** 10227528
- **Project number:** 3P30CA060553-27S2
- **Recipient organization:** NORTHWESTERN UNIVERSITY
- **Principal Investigator:** LEONIDAS C. PLATANIAS
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $302,248
- **Award type:** 3
- **Project period:** 1997-08-15 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10227528

## Citation

> US National Institutes of Health, RePORTER application 10227528, Implementation and Evaluation at Northwestern Medicine of Shareable EHR Treatment Plans in support of Multi-Site Clinical Trials (3P30CA060553-27S2). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10227528. Licensed CC0.

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