# Human immune signatures of Dengue virus and Mycobacterium Tuberculosis exposure in infection, disease and vaccination

> **NIH NIH U19** · LA JOLLA INSTITUTE FOR IMMUNOLOGY · 2020 · $292,800

## Abstract

Our group has developed a set of data standards over the years to capture different aspects of immune
profiling studies that enable the description of, for example, the immune exposure being studied (e.g. type
and course of infection or vaccination) or the molecular markers measured in a cytometry assay and how
they relate detected cells to specific cell types. These standards were primarily developed for the Human
Immunology Project Consortium (HIPC), and were tailored to be interoperable with the ImmPort submission
system, in which they have been adopted and are now used for all data submissions into ImmPort. For
HIPC, these standards have enabled cross-center data analysis projects and method development. As part
of this work, automated validation routines have been created that test ImmPort data submissions for their
adherence to these data standards, which has enabled us to identify and correct issues in data
submissions..

## Key facts

- **NIH application ID:** 10228367
- **Project number:** 3U19AI118626-06S1
- **Recipient organization:** LA JOLLA INSTITUTE FOR IMMUNOLOGY
- **Principal Investigator:** Alessandro Sette
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $292,800
- **Award type:** 3
- **Project period:** 2020-09-02 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10228367

## Citation

> US National Institutes of Health, RePORTER application 10228367, Human immune signatures of Dengue virus and Mycobacterium Tuberculosis exposure in infection, disease and vaccination (3U19AI118626-06S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10228367. Licensed CC0.

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