# 2021 Wnt Signaling GRC/GRS

> **NIH NIH R13** · GORDON RESEARCH CONFERENCES · 2022 · $10,000

## Abstract

Project Summary
We request partial support for the Gordon Research Conference (GRC) and Gordon Research Seminar (GRS)
titled ““Wnt Signaling: Molecular Mechanisms, Development andTtissue Homeostasis, and Therapeutics” to be
held August 1-6, 2021 at the Rey Don Jaime Grand Hotel in Castelldefels, Spain. This meeting will be chaired
by Stephane Angers (University of Toronto, Canada) and Mariann Bienz (MRC, UK) with Ken Cadigan
(University of Michigan, USA) and Madelon Maurice (UMC Utrecht, Netherlands) as Vice-Chairs., and will include
presentations from many prominent scientists, at varied career stages, active in the field of Wnt biology. The
GRS will be held at the same location July 31-August 1, 2021 and will feature talks from up and coming graduate
students and postdoctoral fellows and will be led by postdoctoral fellows Rony Chidiac (University of Toronto)
and Pooja R. Sonavane (USCD). The specific aim of the conference is to provide a forum for the presentation
and discussion of recent advances and new ideas in all aspects of Wnt biology. Progress in this field has
consistently accelerated and has touched on countless biological processes in all metazoan life forms. In
addition, the Wnt pathway is widely recognized as a critical regulator of tissue homeostasis, and, consequently,
its de-regulation is associated with many disorders, from early developmental abnormalities to age-related
diseases, such as cancer.
Session topics have been selected on the basis of their potential impact on the key current scientific questions
in development, stem cell biology and cancer. The meeting is structured to include sessions on the mechanisms
of Wnt signal transduction, structure and function of Wnt signaling, Wnt signaling in tissue engineering and
organoids, Wnt signaling in diseases, Wnt signaling in Development, bcatenin-independent Wnt signaling, Wnt
signaling in stem cells, tissue homeostasis and regeneration and Therapeutic targeting of Wnt signaling. Insights
into the Wnt function will be gleaned from a broad spectrum of model organisms, including hydra, worms, flies,
frogs, fish and mice. The diversity of scientists gathering at this meeting along with the broad spectrum of topics
will not only provide a fertile learning environment that will certainly benefit all attendees, but will also lead to
new insights, interactions and future collaborations that will push the boundaries of biomedical research.
The main long-term goal of this GRC is to raise our understanding of this complex and critical signaling pathway
and thereby contribute to the continuous development of methods to target and manipulate this pathway for
eventual therapeutic interventions of currently incurable diseases.

## Key facts

- **NIH application ID:** 10229196
- **Project number:** 1R13HD105309-01
- **Recipient organization:** GORDON RESEARCH CONFERENCES
- **Principal Investigator:** KENNETH M CADIGAN
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $10,000
- **Award type:** 1
- **Project period:** 2022-09-01 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10229196

## Citation

> US National Institutes of Health, RePORTER application 10229196, 2021 Wnt Signaling GRC/GRS (1R13HD105309-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10229196. Licensed CC0.

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