# The Hemostasis, Thrombosis, and Inflammation Models Core

> **NIH NIH P01** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2021 · $347,451

## Abstract

Abstract 
The Hemostasis, Thrombosis, and Inflammation Models Core (Core A) will provide the resources, equipment 
and technical expertise to conduct the in vivo assays that are a critical component of all projects included in this 
program. 
The main services provided by the core are: 
1. Organize shipment of mice from UC San Diego to UNC Chapel Hill and to establish colonies for select strains 
 at UNC Chapel Hill 
2. Subject mice to various models of hemostasis, thrombosis, and inflammation 
3. Analyze data and provide project investigators with results and feedback on how to move forward with 
 projects/ mouse model studies. 
Including an animal models core will increase reproducibility in results obtained for the various projects in this 
PPG, and drastically reduce costs for labor and set-up/ maintenance of major equipment. Core A will be directed 
by Dr. Wolfgang Bergmeier, an Associate Professor of Biochemistry and Biophysics at the University of North 
Carolina who has many years of expertise in the use of animal models (Hemostasis, Thrombosis, and 
Inflammation) and state-of-the-art intravital microscopy (IVM) imaging techniques. In his own research, he has 
made seminal contributions to our understanding of how the small GTPase Rap1 and its regulators affect platelet 
and neutrophil functions – a major focus area of this program.

## Key facts

- **NIH application ID:** 10229367
- **Project number:** 5P01HL151433-02
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** Wolfgang Bergmeier
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $347,451
- **Award type:** 5
- **Project period:** 2020-08-05 → 2025-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10229367

## Citation

> US National Institutes of Health, RePORTER application 10229367, The Hemostasis, Thrombosis, and Inflammation Models Core (5P01HL151433-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10229367. Licensed CC0.

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