# Flow Cytometry and High Throughput Screening Shared Resource

> **NIH NIH P30** · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2020 · $6,765

## Abstract

FLOW CYTOMETRY & HIGH THROUGHPUT SCREENING SHARED RESOURCE 
ABSTRACT 
The UNMCC Flow Cytometry and High Throughput Screening Shared Resource (Flow Cytometry-HTS) provides 
UNMCC and other researchers with state-of-the-art instruments, infrastructure and expertise. The Resource, 
directed by Bruce Edwards, PhD and managed by Mark Carter, MS, provides cell analysis, cell sorting, and 
offline data analysis as standard services. Resource users are individually trained in instrument and software 
use. Current charge back rates to Resource users are in the low to mid-range of rates nationwide. The Resource 
also has a history of innovation: The Resource and members of the UNMCC Cancer Therapeutics (CT) Research 
Program (Sklar & B. Edwards) invented the capability to conduct high throughput screens using a flow cytometric 
platform (commercialized as HyperCyt in 2006), which led to creation of a full-fledged High Throughput 
Screening Center: The UNM Center for Molecular Discovery (CMD), which is affiliated with the Resource. In the 
past project period, the Resource has worked to facilitate access to CMD for UNMCC members as well as 
collaborators at other NCI Cancer Centers and HyperCyt high throughput screening as a technical service, 
allowing Resource users routine access to novel high throughput screening technologies. The Resource 
supports small scale screening projects for investigators who have already developed targets that are ready for 
screening in 96- or 384-well plates. The Resource also serves as a conduit for pilot projects funded from local 
resources to evolve into larger, NIH-supported screening projects in the CMD. This highly productive strategy 
has allowed UNMCC Program members to identify potent small molecule probes for estrogen receptors, 
GTPases, formyl peptide receptors and efflux transporters, as well as a number of approved drugs that could be 
repurposed for new clinical applications. The Resource also provides easily accessible reservation and billing 
systems. To promote excellence in research, the Resource provides UNMCC Program members and trainees 
with expert assistance and information to facilitate development of cell analysis and discovery projects in support 
of grant applications and publications. A Resource priority is to integrate advanced technologies developed by 
the CMD and UNMCC Research Programs into its operations to make them more broadly available to the 
research community. Education and dissemination activities include: participation in production of a UNM Shared 
Resource newsletter, workshops and presentations on specialized topics pertaining to flow cytometry and drug 
discovery, ad hoc facility tours for students and faculty, and a Resource web page to advertise upcoming events 
and Resource instruments, services and fees. During the previous 5-yr project period, 48 UNMCC members 
from 4 UNMCC Research Programs used the Resource, resulting in a total of 97 publications, of which 15 are 
pres...

## Key facts

- **NIH application ID:** 10230655
- **Project number:** 3P30CA118100-15S9
- **Recipient organization:** UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- **Principal Investigator:** CHERYL LYNN WILLMAN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $6,765
- **Award type:** 3
- **Project period:** 2005-09-26 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10230655

## Citation

> US National Institutes of Health, RePORTER application 10230655, Flow Cytometry and High Throughput Screening Shared Resource (3P30CA118100-15S9). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10230655. Licensed CC0.

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