# FASEB's The Lysophospholipid and Related Mediators Conference: From Bench to Clinic

> **NIH NIH R13** · FEDERATION OF AMER SOC FOR EXPER BIOLOGY · 2021 · $23,500

## Abstract

Abstract
The FASEB Science Research Conference on Lysophospholipid and Related Mediators: From Bench to Clinic
will be held July 11 - July 16, 2021 at the Grand Hotel Malahide, Ireland. This conference will address current
research and emerging concepts related primarily to the lysophospholipids sphingosine 1-phosphate (S1P) and
lysophosphatidic acid (LPA) and their roles in health and disease. S1P and LPA are signaling lipids that activate
5 and 6 G protein-coupled receptors, respectively, and bind to intracellular target proteins to regulate cell biology.
These biological interactions control vital functions in the cardiovascular system, the immune system, and the
nervous system. These lipids are important in pulmonary fibrosis, atherosclerosis, cancer, autoimmunity, and
other disease states. Both receptors and enzymes regulating lysophospholipid metabolism have been shown to
function as potential therapeutic targets to diagnose, prevent or treat disease. The conference will emphasize the
translation of this work into clinical practice and highlight the research advances being made at a rapid pace by
many new investigators in this field. The meeting provides a unique and invaluable forum for scientists from
diverse disciplines to meet and discuss their latest research findings. The conference aims are to 1) provide
intellectual exchange between scientists and trainees from multiple disciplines engaged in lysophospholipid
research; 2) encourage and facilitate active discussion between early career and new investigators and
established scientists via interactive career workshops and multiple opportunities for networking/collaboration;
and 3) provide a platform to promote the participation of women and underrepresented minorities. The conference
will allow diverse early career and established investigators to communicate late-breaking research results and
promote future interactions aligned with developing therapies for diseases in which lysophospholipids play a
predominant role. The conference site in Ireland will facilitate maximum participation of European scientists,
scientists from other countries abroad, and US counterparts to promote productive interactions focusing on the
translational implications of lysophospholipids.

## Key facts

- **NIH application ID:** 10231613
- **Project number:** 1R13HL158089-01
- **Recipient organization:** FEDERATION OF AMER SOC FOR EXPER BIOLOGY
- **Principal Investigator:** Susan Ruth Schwab
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $23,500
- **Award type:** 1
- **Project period:** 2021-04-15 → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10231613

## Citation

> US National Institutes of Health, RePORTER application 10231613, FASEB's The Lysophospholipid and Related Mediators Conference: From Bench to Clinic (1R13HL158089-01). Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/grant/nih/10231613. Licensed CC0.

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