# Core D  Microbial Community Analysis Core

> **NIH NIH P01** · HENRY FORD HEALTH SYSTEM · 2021 · $385,652

## Abstract

Core D will provide microbial community compositional profiling for Projects 1, 2, 3 and 4 with next-
generation biomarker sequencing. Having a centralized processing core for sequencing will reduce variation
due to sample processing during gDNA extraction, PCR amplification, sequencing steps and data
normalization. Core D is highly qualified to perform such assays as is exemplified by the data generated and
published in our previous collaborative projects and preliminary data. These studies have allowed us to
demonstrate that vertical transfer of maternal microbiome to her infant occurs and that pioneer communities
associate with distinct microbiome developmental trajectories in high-risk-for-asthma infants compared to low-
risk controls. Core D has the personnel expertise, equipment and capacity to provide timely high-throughput
microbial sequencing to all four projects in this application.

## Key facts

- **NIH application ID:** 10232176
- **Project number:** 5P01AI089473-08
- **Recipient organization:** HENRY FORD HEALTH SYSTEM
- **Principal Investigator:** Susan Veronica Lynch
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $385,652
- **Award type:** 5
- **Project period:** 2012-07-06 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10232176

## Citation

> US National Institutes of Health, RePORTER application 10232176, Core D  Microbial Community Analysis Core (5P01AI089473-08). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10232176. Licensed CC0.

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