# Biomechanics, Biomaterials and Multimodal Tissue Imaging Core (BBMTI Core)

> **NIH NIH P30** · UNIVERSITY OF ROCHESTER · 2022 · $233,866

## Abstract

The Biomechanics, Biomaterials, and Multimodal Tissue Imaging (B2MTI) Core is an indispensable catalyst for
efficiency and innovation in the University of Rochester Resource-based Center for Bone, Muscle and
Orthopaedic Research (ROCSTARR). Over the past 9 years, the B2MTI Core utilized state-of-the-art
equipment to provide scientific services, including biomechanical testing, biomaterials synthesis, fabrication
and characterization, as well as preclinical and medical imaging in models of musculoskeletal pathologies and
repair. In this renewal application, we will continue to provide ROCSTARR investigators with the scientific
expertise and services that meet the standards of efficiency, scientific rigor, and reproducibility. In addition, we
will foster the development of innovative technologies by the ROCSTARR Investigators to catalyze funding and
cultivate collaborative research programs that address the challenges that impact musculoskeletal health. Our
Aims include: 1) providing services and facilitating innovations in biomechanical testing at multiple scales in
models of orthopaedic trauma and disease, as well as supporting clinically relevant cadaveric studies of
surgical implants and repair procedures; 2) supporting innovations in biomaterials for drug and cell delivery and
expanding the scope of biomaterials integration into novel microphysiological models of musculoskeletal
tissues and systems (e.g., tissue chips); 3) supporting multimodal preclinical imaging including micro-CT,
multispectral (fluorescence and bioluminescence), near infrared, and ultrasound imaging, and exploring
innovations in other imaging modalities including Raman Spectroscopy and Diffuse Correlation Tomography
for applications in the assessment of bone quality and fracture repair; 4) integrating expert ROCSTARR faculty
as Advisors in specialty Sub-Cores to offer conceptual and technical guidance and expanded access to novel
technologies; and 5) interacting with the Core Users Committee to maintain cost-effective access to Core
resources and supporting the Admin Core’s Enrichment initiatives including the P30 Pilots and the new
Discovery Fund. Over the past 9 years, the B2MTI Core has proven the added value of integrating its services
to overcome the inefficiencies of uncoordinated efforts from multiple ROCSTARR laboratories, and has had a
measurable impact on the research programs of NIH-funded and New/Early Stage ROCSTARR Investigators.
The B2MTI Core will continue to foster collaborative funding and high impact scientific publications that
advance musculoskeletal discoveries and innovations from the bench to the bedside.

## Key facts

- **NIH application ID:** 10232836
- **Project number:** 2P30AR069655-06
- **Recipient organization:** UNIVERSITY OF ROCHESTER
- **Principal Investigator:** Hani A Awad
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $233,866
- **Award type:** 2
- **Project period:** 2022-01-01 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10232836

## Citation

> US National Institutes of Health, RePORTER application 10232836, Biomechanics, Biomaterials and Multimodal Tissue Imaging Core (BBMTI Core) (2P30AR069655-06). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10232836. Licensed CC0.

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