# Power Hungry: Fuel Cells Harvesting Biofluids for Renewable Power of Wearable Medical Devices

> **NIH VA I21** · VA EASTERN COLORADO HEALTH CARE SYSTEM · 2021 · —

## Abstract

Our ultimate goal is to create an alkaline fuel cell that uses blood sugars as a renewable power source for
implantable and wearable medical devices. We believe the components and technologies needed to create such
a device have come of age and that an opportunity exists to develop a system that integrates these components
to produce a clinically viable system in terms of size, power, and efficiency. If successful, this will be a completely
novel technology using blood sugar as a fuel source for an alkaline fuel cell. A fuel cell of this nature would
enable long-term, renewable power for implanted and/or wearable medical devices. Circuits with super-
capacitors or rechargeable batteries will help with power management4. In its final formulation, it is possible to
envision a small spiral wound membrane-based fuel cell packaged into a device the size of three AA batteries
that uses body-harvested sugars to produce electrical power for medical devices.
 For the purpose of this SPiRE development project as a first step we propose to develop an external glucose-
based fuel cell as a technology demonstrator. Such a system might have advantages over standard battery
technology in terms of energy density, size, and weight but the real goal is to allow us to research and address
the pitfalls surrounding implementation of this technology and to enable us to have discussions with clinicians,
such as vascular surgeons and the like, on how to best advance and deploy this technology in people. For this
SPiRE award. We will:
 • Create a bench-top fuel cell using off-the-shelf materials, an anion exchange membrane, and electronics.
 • Develop an intrinsic fuel cell architecture using glucose as a fuel source as a proof-of-concept.
 The methods of this project build upon existing technical expertise, collaborations, and equipment already
used by Dr. Weir’s and Dr. Pellegrino’s research groups. We will implement an alkaline electrolyte rather than
the typical acid electrolyte. The alkaline electrolyte in our experiment is a solid polymer electrolyte known as an
anion exchange membrane (AEM). Anion exchange membranes (AEM) offer benefits over traditional proton
exchange membranes (PEM). Anion exchange membranes do not require noble metal catalysts and have low
fuel crossover. AEM’s also have been shown to have high power density when compared to proton exchange
membrane (PEM) glucose fuel cells.
 In our study, we will use a highly ionically conductive AEM developed and provided by Dr. Chulsung Bae of
Rensselaer Polytechnic Institute (RPI). This state-of-the-art membrane will reduce the need for a basic glucose
media enabling in-vivo or ex-vivo bio-medical applications. Our membrane electrode assembly, consisting of the
anode, cathode, and AEM, will be placed in a standard 10 cm2 fuel cell stack. We completely acknowledge that
the route to fully implantable fuel cells must pass through other hurdles, such as biocompatibility; nonetheless,
the current materials advan...

## Key facts

- **NIH application ID:** 10237207
- **Project number:** 5I21RX003471-02
- **Recipient organization:** VA EASTERN COLORADO HEALTH CARE SYSTEM
- **Principal Investigator:** Richard Fergus ffrench Weir
- **Activity code:** I21 (R01, R21, SBIR, etc.)
- **Funding institute:** VA
- **Fiscal year:** 2021
- **Award amount:** —
- **Award type:** 5
- **Project period:** 2020-10-01 → 2022-09-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10237207

## Citation

> US National Institutes of Health, RePORTER application 10237207, Power Hungry: Fuel Cells Harvesting Biofluids for Renewable Power of Wearable Medical Devices (5I21RX003471-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10237207. Licensed CC0.

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