# Clinical Core

> **NIH NIH P30** · SEATTLE CHILDREN'S HOSPITAL · 2021 · $235,676

## Abstract

PROJECT SUMMARY/ABSTRACT
The Clinical Core provides both services and expertise and has a strong training component for cystic fibrosis
(CF) research. The services focus on regulatory support, and study design and conduct support. We serve as
a local, National and International resource to collaborators for advanced clinical trial design and conduct,
biostatistical and epidemiologic methods and comparative effect research methods including cost-effectiveness
analysis. The Core supports the central aims of the UW Cystic Fibrosis Research and Translation Center
(CFRTC): to use highly effective modulator therapy (HEMT) initiation to discover novel aspects of cystic
fibrosis (CF) pathophysiology, define the clinical manifestations and best treatment approaches for the “new”
disease that CF will become, and perform basic and translational research on disease aspects that persist
despite HEMT. Further, the CC fosters collaboration across the CFRTC biomedical cores to enhance
translational research through the sharing of existing and development of expanded human and bacterial
repositories linked to clinical databases that enable development of improved assays and clinical outcome
measures. We are well positioned to continue to advance novel therapeutics through the drug development
pipeline and transition to major studies in CF that focus on improving our understanding of the disease in the
setting of advancing therapeutics – specifically HEMT that will forever change the clinical landscape in CF.

## Key facts

- **NIH application ID:** 10237342
- **Project number:** 5P30DK089507-12
- **Recipient organization:** SEATTLE CHILDREN'S HOSPITAL
- **Principal Investigator:** Christopher Hooper Goss
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $235,676
- **Award type:** 5
- **Project period:** 2010-07-06 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10237342

## Citation

> US National Institutes of Health, RePORTER application 10237342, Clinical Core (5P30DK089507-12). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10237342. Licensed CC0.

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