# Innovative Vaccine Approaches

> **NIH NIH R13** · KEYSTONE SYMPOSIA · 2021 · $8,000

## Abstract

ABSTRACT
Support is requested for a Keystone Symposia conference entitled Innovative Vaccine Approaches, organized
by Drs. Mariagrazia Pizza, Galit Alter and Gordon Dougan. The conference will be held in Vancouver, Canada
from June 27- July 1, 2021.
Vaccines have the power to prevent and potentially eradicate a wide range of infectious diseases, representing
one of the most effective life-saving measures at our disposal against global health threats. The recent
coronavirus pandemic has brought the importance and urgency of vaccine development efforts into sharp
focus. Moreover, the vaccinology field is evolving very rapidly, thanks to advances in our understanding of
microbiology, immunology and genomics, as well as advances in structural analysis of antigens and antigen-
antibody complexes and impacts of variation. Over the years, this field has also experienced an elucidation of
mechanisms of immunity and protection, and identification of correlates. However, many questions are still
unsolved and innovative approaches are needed to address new vaccine challenges like antimicrobial
resistance, emerging infectious diseases, cancer and diseases associated with our aging population. This
conference will cover the latest advances and novel approaches towards vaccine development, including: (1)
novel antigen delivery systems; (2) in vitro and in vivo model systems for vaccine appraisal (3) the use of
human challenge models; (4) the role of ‘systems biology’ in the comprehensive analysis of immune correlates,
biomarker identification and safety; (5) machine-learning approaches to define correlations between antibody
repertoires and protection; and (6) strategies for developing low cost vaccines for economically challenged
populations. Together these topics will provide attendees with the new ideas and tools to continue to forge new
frontiers in vaccine capabilities.

## Key facts

- **NIH application ID:** 10237543
- **Project number:** 1R13AI161938-01
- **Recipient organization:** KEYSTONE SYMPOSIA
- **Principal Investigator:** Thale Cross Jarvis
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $8,000
- **Award type:** 1
- **Project period:** 2021-06-23 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10237543

## Citation

> US National Institutes of Health, RePORTER application 10237543, Innovative Vaccine Approaches (1R13AI161938-01). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10237543. Licensed CC0.

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