# Clinical Study of Avmacol for Detoxification of Tobacco Carcinogens in Heavy Smokers

> **NIH NIH N01** · UNIVERSITY OF ARIZONA · 2020 · $44,794

## Abstract

The dietary supplement Avmacol contains precursors of sulforaphane, a broccoli extract that is an inducer of carcinogen metabolism.  The proposed clinical trial shall address whether treatment with Avmacol, either 4 or 8 tablets per day, results in enhanced detoxification of tobacco-related carcinogens in healthy current smokers. The ultimate goal is to determine if this supplement can be used for prevention of tobacco-related malignancies, such as head and neck or lung cancer.

## Key facts

- **NIH application ID:** 10237826
- **Project number:** 261201200031I-P00003-26100012-1
- **Recipient organization:** UNIVERSITY OF ARIZONA
- **Principal Investigator:** Sherry Chow
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $44,794
- **Award type:** —
- **Project period:** 2017-09-15 → 2021-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10237826

## Citation

> US National Institutes of Health, RePORTER application 10237826, Clinical Study of Avmacol for Detoxification of Tobacco Carcinogens in Heavy Smokers (261201200031I-P00003-26100012-1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10237826. Licensed CC0.

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