# High-throughput systematic characterization of regulatory element function

> **NIH NIH UM1** · STANFORD UNIVERSITY · 2021 · $1,032,594

## Abstract

Project Summary
This application is an administrative supplement request for 5UM1HG009436. The ENCODE project has
produced high-resolution, high-quality maps of components of the `regulome' in a set of tissues and cell lines,
identifying a collection of putative regulatory elements. Our proposal aims to generate and release data that
test the functional relevance of these putative elements with high-throughput, pooled CRISPR screens, as well
as a number of other methods that are aimed to understand the relationship between transcription factor
levels, global accessibility at regulatory elements, an the effects on gene expression.

## Key facts

- **NIH application ID:** 10238366
- **Project number:** 3UM1HG009436-04S1
- **Recipient organization:** STANFORD UNIVERSITY
- **Principal Investigator:** MICHAEL C BASSIK
- **Activity code:** UM1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,032,594
- **Award type:** 3
- **Project period:** 2020-09-01 → 2022-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10238366

## Citation

> US National Institutes of Health, RePORTER application 10238366, High-throughput systematic characterization of regulatory element function (3UM1HG009436-04S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10238366. Licensed CC0.

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