# COORDINATING CENTER TO HELP ELIMINATE/REDUCE ORAL HEALTH INEQUALITIES IN CHILDREN

> **NIH NIH U01** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2020 · $688,336

## Abstract

The proposed “Coordinating Center to Help Eliminate/Reduce Oral health Inequalities in
Children" (CC HEROIC; CC for short) will provide collaborative research and coordinating
center expertise and services to 8 two-phase UH2/UH3 NIDCR-funded community-engaged
projects (RFA-DE-15-006) to assess multilevel interventions, programs or policies to reduce or
eliminate oral health disparities in diverse, vulnerable populations of children aged 0 to 21
years.. The UH2/UH3 project PD/PIs, the NIDCR, and the CC will form a collaborative research
consortium. The 8 projects will address a range of multilevel mechanisms of action with
multidisciplinary teams. The proposed CC investigator and staff team possesses relevant
transdisciplinary expertise in oral health, social and behavioral sciences, microbiology, genetics,
epidemiology, health policy, health economics, and biostatistics, plus data coordinating center
experience serving multiple health and oral health projects within NIH research consortia. As
the NIDCR Early Child Caries Collaborating Centers Data Coordinating Center (NIDCR EC4
DCC) the team has demonstrated its ability to collaboratively and creatively support large-scale,
clinically-relevant, and community-engaged oral health disparities research simultaneously in 6
UH2-like studies and then in 4 UH3-like randomized clinical trials in 6 institutions across 3 time
zones to meet the overall scientific and project community partner goals. We will utilize both the
NHLBI Compendium of Best Practices for Data Coordinating Centers as well as the Community-
Campus Partnership in Health's Position Statement on Authentic Partnerships. The CC will
establish ongoing, collaborative relationships with each UH2/UH3 project to provide services
and expertise in the following areas: (a) oral health-related clinical knowledge; (b) qualitative
and quantitative research design with particular emphasis on oral health outcomes in diverse,
community-based, pediatric populations; (c) selecting cost measures and designing cost
analyses; (d) selecting, developing, and refining measurement instruments, including
harmonizing measures across the 8 UH2/UH3 projects; (e) informatics, including providing
secure, customized data acquisition systems and project and clinical research management
systems; (f) training in the use of those systems; (g) participant safety monitoring and reporting
to the project investigators, NIDCR, the clinical operations contractor, and an independent Data
and Safety Monitoring Board (DMSB); (h) data management, processing, and quality control; (i)
developing qualitative and quantitative data analysis plans; (j) reporting on project progress to
the project investigators, NIDCR, and the Data and Safety Monitoring Board; and (k) coordinate
and participate in consortium meetings including regular Steering Committee, ad hoc
Collaborating Working Group, and annual External Scientific Advisory Committee (ESAC)
meetings. Our experienced children's oral hea...

## Key facts

- **NIH application ID:** 10238473
- **Project number:** 3U01DE025507-05S2
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** STUART A GANSKY
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $688,336
- **Award type:** 3
- **Project period:** 2020-09-01 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10238473

## Citation

> US National Institutes of Health, RePORTER application 10238473, COORDINATING CENTER TO HELP ELIMINATE/REDUCE ORAL HEALTH INEQUALITIES IN CHILDREN (3U01DE025507-05S2). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10238473. Licensed CC0.

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