# Clinical Core

> **NIH NIH P30** · HARVARD UNIVERSITY · 2021 · $323,170

## Abstract

PROJECT SUMMARY/ABSTRACT 
Clinical Core (Core C) 
The mission of the HU CFAR is to expand, promote, and facilitate collaborative innovative multidisciplinary 
HIV/AIDS research among its members to bring an end to the HIV epidemic. Critical to this mission is the 
Clinical Core, which provides essential resources to support and foster clinical and translational research 
among clinical, social, behavioral, and basic scientists. The primary goals of the Clinical Core are to facilitate 
access to clinical research databases, to provide regulatory support to CFAR investigators, to integrate access 
mechanisms for acquiring and storing blood and tissue samples from people living with HIV, and to catalyze 
collaborative cohort studies. These efforts include close linkages to and communication with HIV affected 
communities and engagement of research participants in populations disproportionately affected by HIV. The 
impact of the Clinical Core extends well beyond Boston, by providing a linkage to multiple international sites of 
Harvard-based HIV/AIDS research and through a series of innovative and wide-ranging educational programs 
designed to facilitate clinical research. The components of translational research supported by the HU CFAR 
Clinical Core are either not funded or are only inadequately funded by other support mechanisms, and thus the 
value added of this Core has been immense. 
While the mission of the Clinical Core remains to facilitate clinical and translational research, the Core 
continues to evolve and modify its programs to meet the emerging needs of investigators. Among new 
initiatives outlined in this proposal are: a) expansion of HIV cohorts available to investigators, with a special 
focus on high-priority populations and tissue sampling; b) upgrading database infrastructure for clinical cohorts; 
and c) new resources to facilitate interactions with the community and collaborations. To meet the ongoing 
needs of CFAR investigators, we will accomplish the following specific aims: 
1. To expand essential infrastructure support for HU CFAR investigators conducting clinical and basic 
 science research related to HIV infection, HIV-associated comorbidities and coinfections, populations 
 disproportionately impacted by HIV, and HIV prevention. 
2. To develop and provide access to databases and clinical specimen repositories from a greater number 
 and variety of well-characterized HIV cohorts. 
3. To support novel educational and outreach programs designed to facilitate clinical and translational 
 research at HU, HU CFAR-associated sites and CFAR-affiliated international sites.

## Key facts

- **NIH application ID:** 10238747
- **Project number:** 5P30AI060354-18
- **Recipient organization:** HARVARD UNIVERSITY
- **Principal Investigator:** Jonathan Li
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $323,170
- **Award type:** 5
- **Project period:** 2004-07-01 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10238747

## Citation

> US National Institutes of Health, RePORTER application 10238747, Clinical Core (5P30AI060354-18). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10238747. Licensed CC0.

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