IGF::OT::IGF STATIN THERAPY TO REDUCE DISEASE PROGRESSION FROM LIVER CIRRHOSIS TO CANCER

NIH RePORTER · NIH · N01 · $162,356 · view on reporter.nih.gov ↗

Abstract

The proposed study is a Phase IIb, double-blinded, placebo-controlled trial of a statin to evaluate the impact of statin treatment on disease progression in 80 patients with liver cirrhosis who have a current Model for End-Stage Liver Disease (MELD) ≤ 20 and no evidence of Hepatocellular carcinoma (HCC). Participants shall be recruited from hepatology clinics at Cedar Sinai Medical Center (CSMC) and Northwestern University (NWU) and shall include patients who are currently waitlisted, or under evaluation, for a liver transplant.

Key facts

NIH application ID
10240245
Project number
261201200035I-P00004-26100012-1
Recipient
NORTHWESTERN UNIVERSITY
Principal Investigator
SEEMA KHAN
Activity code
N01
Funding institute
NIH
Fiscal year
2020
Award amount
$162,356
Award type
Project period
2016-09-15 → 2022-04-13