# P30 Core Grant for Vision Research

> **NIH NIH P30** · MASSACHUSETTS EYE AND EAR INFIRMARY · 2021 · $172,445

## Abstract

Project Summary- Genomics Core
Genomic technologies have broadly impacted vision science and have a crifical role in most ofthe
research programs carried out at Mass Eye and Ear. The Genomics core provides access to state-of-
the-art genomic resources at low cost. Direct access to the Genomics core resources and expertise
makes it possible for investigators to efficiently obtain high-quality data and eliminates the long
queues for services such as next-generation sequencing frequently experienced at off-site centers.
Importantly, the expert Genomics core personnel can help investigators plan appropriate experiments
and assist with analyses (including troubleshooting)-services that would not be readily available
elsewhere. The efficient timeline for data acquisition increases the overall productivity of the core
investigators as well as improves the quality of the research. Genomic data is an important feature of
many of the MEEI research programs and is especially important for the translational studies. The
Genomics core personnel are experts in the genetics and genomics of eye disease, creating
opportunities for collaboration among investigators using this resource. Overall direct access to
Genomics core personnel and resources greatly enhances the quality of the research and ultimate
accomplishments of the core investigators. The Genomics core is directed by Dr. Eric Pierce, an
expert in the genetics and genomics of inherited ocular disease. Services provided by the Genomics
core includes: Sanger sequencing, whole exome sequencing, selective exon capture and next
generation sequencing (NGS) for ocular disease genes (RetNeT, glaucoma, optic neuropathy,
mitochondrial DNA), genome-wide genotyping (both common and rare variation), copy number
variation (CNV) using array CGH (comparative genomic hybridization), high-density genotypes and
MLPA (multiplex ligation-dependent probe amplification), and RNA sequencing (RNA-seq) for
transcriptome analyses.

## Key facts

- **NIH application ID:** 10240746
- **Project number:** 5P30EY014104-18
- **Recipient organization:** MASSACHUSETTS EYE AND EAR INFIRMARY
- **Principal Investigator:** Eric A Pierce
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $172,445
- **Award type:** 5
- **Project period:** 2002-09-01 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10240746

## Citation

> US National Institutes of Health, RePORTER application 10240746, P30 Core Grant for Vision Research (5P30EY014104-18). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10240746. Licensed CC0.

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