# Administrative Core

> **NIH NIH U19** · UNIVERSITY OF PENNSYLVANIA · 2021 · $411,397

## Abstract

ADMINISTRATIVE CORE
The Administrative Core of this U19 Center will be responsible for coordinating all activities associated
with the CW2IP2. This will include the scheduling of the biweekly calls of the Center Executive Steering
Committee and the monthly joint call with the members of the Clinical Core. The Administrative Core will
also organize the bi-annual conference call and annual meeting of the External Liaison Committee. The
Administrative Core will provide the oversight needed to direct the efficient operation of the CW2IP on a
day-to-day basis, such as the shipment of research materials between the different labs involved in the
consortium. The Administrative Core will also provide financial oversight of the U19 Center. The core
will be directed by Robert H. Mach, Ph.D. the Director of this U19 Center application.
Given the multi-site structure of the Medicinal Chemistry and Radiochemistry (MCRC) Core, a key
component of the Administrative Core is the Center Executive Steering Committee, which consists of the
site P.I.s of the MCRC core. The Executive Steering Committee will meet via video teleconference on a
biweekly basis to provide updates on the compound screening and medicinal chemistry studies. The
Executive Steering Committee will be responsible for identifying which compounds identified as hits will
be chosen for full evaluation in structure-activity relationship studies. Another function of the biweekly
conference calls is to review upcoming milestones, and to determine if the U19 Center project is on track
for achieving the milestones. The Administrative Core will also be responsible for the obtaining regulatory
approval for the PET radiotracers chosen for translation for first-in-human studies.

## Key facts

- **NIH application ID:** 10241509
- **Project number:** 5U19NS110456-03
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** ROBERT H MACH
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $411,397
- **Award type:** 5
- **Project period:** 2019-09-24 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10241509

## Citation

> US National Institutes of Health, RePORTER application 10241509, Administrative Core (5U19NS110456-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10241509. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*