# Core C - Biostatistics and Data Mangement Core

> **NIH NIH P01** · UNIVERSITY OF PENNSYLVANIA · 2021 · $119,225

## Abstract

Core C (Biostatistics, Bioinformatics, and Data Management)
Abstract
Core C (Biostatistics, Bioinformatics, and Data Management) provides expert guidance and collaboration in the
biostatistical, bioinformatics, and data management aspects of the design, conduct and analysis of
translational research projects generated by this P01 proposal. In order to achieve these goals, the specific
aims of Core C include: 1) to consult with project investigators to select efficient study designs and sample
sizes that are adequate to address study objectives, 2) to work with investigators to prepare tables and graphs,
to execute efficient and robust statistical and bioinformatics analyses, to draft statistical sections of project
manuscripts, and to propose and implement best design and analysis strategies for subsequent studies, and 3)
to provide statistical support in data management for clinical trials, projects, and cores, and promote data
sharing. Specifically, prior to the initiation of studies, Core staff members will consult with project investigators
to help select designs that are efficient and adequately powered. For the proposed clinical trials, Core C will
collaborate to utilize existing data management systems or establish new ones if required, and design case
report forms (CRF) that collect all required information in an unambiguous way. As studies proceed, staff
members review data periodically to evaluate adherence to study procedures, data quality, and adequacy of
underlying statistical assumptions. When studies are finished, staff members review the data again, produce
informative summary tables and graphical displays, conduct correct and efficient statistical and bioinformatics
analyses, and consult on the design of subsequent studies. The work of Core C involves close integration with
the efforts of all the research projects. Core C staff members have extensive experience supporting cancer
research, with strong backgrounds in basic science, translational research, clinical trials, bioinformatics,
research computing, and data management. With their many years of experience in biomedical research, they
stand ready to identify and apply ideal methods for the design and analysis, and data management of the
proposed research studies. Core C offers its services to all projects and cores in this P01 proposal.

## Key facts

- **NIH application ID:** 10241983
- **Project number:** 5P01CA217805-04
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Wei-Ting Hwang
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $119,225
- **Award type:** 5
- **Project period:** 2018-09-14 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10241983

## Citation

> US National Institutes of Health, RePORTER application 10241983, Core C - Biostatistics and Data Mangement Core (5P01CA217805-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10241983. Licensed CC0.

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