# Morris K. Udall Center at the University of Rochester (UR-Udall Center)

> **NIH NIH P50** · UNIVERSITY OF ROCHESTER · 2021 · $1,812,624

## Abstract

SUMMARY
The number of people affected by Parkinson disease (PD) has doubled over the past 25 years and is projected
to double again in the next 25. Current approaches to addressing this “pandemic” are inadequate. Trials are
not informed by disease and simulation models. Participation in research is burdensome and is limited to
individuals who live near research centers. Traditional PD measures are subjective, episodic, and insensitive
resulting in large, long, expensive trials that generate false signals of efficacy, both positive and negative.
A Udall Center at the University of Rochester (UR-Udall Center) will address these barriers and feature the
following:
1. An Administrative Core that supports national research studies, reaches hundreds of thousands, and trains
 the first generation of PD investigators spanning clinical research and computational science
2. An Advanced Analytics Research Core that combines biostatistical and computer science expertise
3. A Clinical Core that will conduct both virtual and in-person PD assessments nationally and locally
4. Four research projects that will address nine NINDS PD 2014 recommendations. These projects will:
 a. Develop predictive disease models and clinical trial simulation tools for the PD research community
 b. Conduct the first U.S. virtual natural history cohort study of LRRK2 carriers
 c. Advance a second-generation smartphone research application (mPower) and calculate a novel mobile
 Parkinson disease score that quantifies PD symptoms from participants anywhere, anytime
 d. Develop passive sensors, including wearable sensors, video analytics, and radio waves, to measure
 the motor and non-motor features of PD in real-world settings
The UR-Udall Center will develop, evaluate, and disseminate novel tools and technologies to accelerate PD
research with an audacious goal of enabling anyone anywhere to participate in research, to benefit from the
resulting therapeutic advances, and to receive care.

## Key facts

- **NIH application ID:** 10242052
- **Project number:** 5P50NS108676-04
- **Recipient organization:** UNIVERSITY OF ROCHESTER
- **Principal Investigator:** Earl Ray Dorsey
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,812,624
- **Award type:** 5
- **Project period:** 2018-09-30 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10242052

## Citation

> US National Institutes of Health, RePORTER application 10242052, Morris K. Udall Center at the University of Rochester (UR-Udall Center) (5P50NS108676-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10242052. Licensed CC0.

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