# Development of Sustainable Reporting to the National COVID Cohort Collaborative (N3C)

> **NIH NIH UL1** · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 2020 · $99,928

## Abstract

Overall-Abstract
San Antonio, positioned at the gateway to South Texas, is the 7th largest US city and the
largest metropolitan area with a minority-majority population. Our 38-county region comprises an impoverished,
rural, and largely Hispanic population with disproportionate rates of diabetes, obesity, and cancer, exacerbated
by lack of health insurance and poor access to care. The region is home to major US military facilities, including
the world’s largest military medical complex. Service members and veterans form populations with special needs.
Neither better access to care nor improved care delivery, on their own, can eliminate health disparities. Innovative
translational research is required to fill knowledge gaps and establish real-world effectiveness to improve health.
In 2006, UT Health Science Center-San Antonio established the Institute for Integration of Medicine &
Science (IIMS) as the academic home for our growing translational science initiatives, training the translational
science workforce, formalizing key strategic partnerships, and creating a community of scholars within a learning
healthcare system. We expanded clinical research programs, dramatically increasing access to clinical trials.
We developed 6 Practice-Based Research Networks that focus on diverse ambulatory populations. We created
6 county-wide Translational Advisory Boards that support engagement through priority setting and matching with
academic investigators. IIMS pioneered IRB process harmonization, resulting in rapid review times and
streamlined pathways to multisite study initiation. We operate a robust pilot grant program, leveraged among our
partners, with a remarkable return on investment. Our workforce development programs, with matriculants
reflecting our diverse population, have graduated 133 masters degree students, supported 27 successful KL2
Scholars and 16 TL1 Scholars, and established de novo a Translational Science PhD program. Our informatics
team has led electronic health record data warehouse development, fostering matches between IIMS
investigators and practice-relevant research priorities. IIMS is now poised to deploy our robust portfolio of
programs across our growing, leveraged, and innovative network of institutional and community partners.
In this proposal, we provide clear strategies to support clinical and translational science across partner
organizations, catalyze research team success, and implement programs that produce creative, collaborative,
and culturally diverse translational scientists. IIMS seeks exceptionalism in translating scientific discoveries
across the T1 to T4 spectrum into improved health care outcomes. Our over-arching Specific Aims are:
 1. Accelerate clinical and translational research innovation and team science along the entire T1 to T4
 research spectrum by providing an academic home integrated with our strategic partner institutions
 2. Expand, diversify, and enhance the workforce of interdisciplinary trans...

## Key facts

- **NIH application ID:** 10244205
- **Project number:** 3UL1TR002645-03S3
- **Recipient organization:** UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- **Principal Investigator:** ROBERT A CLARK
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $99,928
- **Award type:** 3
- **Project period:** 2020-09-22 → 2023-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10244205

## Citation

> US National Institutes of Health, RePORTER application 10244205, Development of Sustainable Reporting to the National COVID Cohort Collaborative (N3C) (3UL1TR002645-03S3). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10244205. Licensed CC0.

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