# Histology, Microscopy, and Imaging Core

> **NIH NIH P30** · CASE WESTERN RESERVE UNIVERSITY · 2021 · $178,574

## Abstract

The goal of the Histology, Microscopy, and Imaging Module is to enhance the capabilities of individual vision
research laboratories by enabling them to conduct studies that require understanding the ocular tissue function
at the cellular level. This goal is accomplished by providing the infrastructure for two types of services -
histology and imaging. The Histology Facility of the Module prepares in a timely fashion cryo or paraffin
sections of eyes and mounts them on slides for histo/immunohistochemistry analyses or laser capture
microdissection. This Facility also conducts routine histological stains. The Microscopy Facility of the Module
helps investigators to produce publication quality images or videos from histological slides, fixed cells, live cells
or in vivo mouse eyes. A physical space, resources, and expertise of the Module, operated and supervised by
highly experienced personnel, serve as the basis for the following Specific Aims: 1) to process, embed, and
section eyes followed by section mounting on slides and staining (if requested); 2) to guide users in the proper
dissection, fixation and staining techniques, thus ensuring the production of high quality histological
specimens; 3) to provide access to Module's microscopes along with training and consultation in all aspects of
a microscopy-based experiments; 4) to provide access to and training on the use of Metamorph imaging
software to properly analyze and generate relevant data from images; 5) to assist in production of publication
quality images and/or videos. The Histology, Microscopy & Imaging Module has the heaviest usage of all P30
Core Grant Modules and will continue assisting VSRC investigators in producing high-quality and high-profile
vision-related publications.

## Key facts

- **NIH application ID:** 10244969
- **Project number:** 5P30EY011373-25
- **Recipient organization:** CASE WESTERN RESERVE UNIVERSITY
- **Principal Investigator:** CARLOS S SUBAUSTE
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $178,574
- **Award type:** 5
- **Project period:** 1997-04-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10244969

## Citation

> US National Institutes of Health, RePORTER application 10244969, Histology, Microscopy, and Imaging Core (5P30EY011373-25). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10244969. Licensed CC0.

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